WikiDer > Immunoglobulin I-set domeni
Immunoglobulin I-set domain
| Immunoglobulin I-set domeni | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
 Fibroblast o'sish omilining tuzilmalari 1.[1] | |||||||||||
| Identifikatorlar | |||||||||||
| Belgilar | Men o'rnatdim | ||||||||||
| Pfam | PF07679 | ||||||||||
| InterPro | IPR013098 | ||||||||||
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Men o'rnatgan domenlar bir nechtasida topilgan hujayra yopishqoqligi molekulalariqon tomirlari, shu jumladan (VCAM), hujayralararo (ICAM), asabiy (NCAM) va mukozal adres (MADCAM) hujayraning adezyon molekulalari, shuningdek tutashgan adezyon molekulalari (JAM). I-setli domenlar bir qator boshqa turli xil protein oilalarida, shu jumladan bir nechta tirozin-protein kinaz retseptorlari, gemolimfa oqsilida mavjud. gemolin, mushak oqsillari titin, telokin va twitchin, neyronlarning adezyon molekulasi aksonin-1,[2] va aksonal rahbarlik, immunitet funktsiyasi va angiogenezda ishtirok etadigan signal molekulasi semaforin 4D.[3]
Ushbu domenni o'z ichiga olgan inson oqsillari
- ADAMTSL1, ADAMTSL3, ALPK3, AXL,
- BOC,
- C9orf94, CADM2, CADM4, CCDC141, CDON, CEACAM7, CHL1, CILP2, CNTN1, CNTN2, CNTN3, CNTN4, CNTN5, CNTN6, CXADR,
- DCC, DSCAM, DSCAML1,
- ESAM,
- FGFR1, FGFR3, FGFR4, FGFRL1, FLT1, FLT4, FSTL4, FSTL5,
- HMCN1, HNT, HSPG2,
- ICAM5, IGFBP7, IGFBPL1, IGSF10, IGSF22, IGSF9, ISLR,
- KALRN, KAZALD1, KDR, KIAA0626, KIRREL, KIRREL2, KIRREL3,
- L1CAM, LINGO1, LINGO2, LRFN2, LRFN3, LRFN4, LRFN5, LRIG1, LRIG2, LRIG3, LRIT2, LRIT3, LRRC24, LRRC4B, LRRC4C, LRRN1, LRRN3, LRRN5, LSAMP,
- MAG, MDGA2, MFAP3L, MUSK, MXRA5, MYBPC1, MYBPC2, MYBPC3, MYBPH, MYBPHL, MYLK, MYOM1, MYOM2, MYOM3, MYOT, MYPN,
- NCAM1, NCAM2, NEGR1, NEO1, KEYINGI, NFASC, NGL1, YOQ, NPHS1, NPTN, NRCAM, NRG2, NT, NTRK2, NTRK3,
- OBSCN, OBSL1, OPCML,
- PALLD, PAPLN, PDGFRA, PRODH2, PTK7, PTPRD, PTPRF, PTPRS, PTPsigma, PUNC,
- ROBO1, ROBO2, ROBO3, ROBO4, ROR1, ROR2,
- SDK1, SDK2, SIGLEC1, SIGLEC6, SPEG,
- TRIO, TTN,
- UNC5A, UNC5B, UNC5C,
- VCAM1, WFIKKN1, WFIKKN2,
Adabiyotlar
- ^ Plotnikov AN, Hubbard SR, Schlessinger J, Mohammadi M (may 2000). "Ikki FGF-FGFR kompleksining kristalli tuzilmalari ligand-retseptorlari o'ziga xosligini aniqlovchi omillarni ochib beradi". Hujayra. 101 (4): 413–24. doi:10.1016 / S0092-8674 (00) 80851-X. PMID 10830168. S2CID 16374022.
- ^ Sonderegger P, Welte V, Diederichs K, Freigang J, Proba K, Leder L (2000). "Axonin-1 / TAG-1 ligandini bog'laydigan modulining kristalli tuzilishi asab hujayralarini yopishtirish uchun fermuar mexanizmini taklif qiladi" (PDF). Hujayra. 101 (4): 425–33. doi:10.1016 / S0092-8674 (00) 80852-1. PMID 10830169. S2CID 15440572.
- ^ Stuart DI, Jones EY, Harlos K, Esnouf RM, Love CA (2006). "Odamning semaforini 4D tuzilishini aniqlash, maqbul bo'lmagan holatlarda MADdan foydalanish misoli". Acta Crystallogr. D.. 62 (Pt 1): 108-15. doi:10.1107 / S0907444905034992. PMID 16369100.
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