WikiDer > Mepindolol

Mepindolol
Klinik ma'lumotlar
ATC kodi	C07AA14 (JSSV) ;
Identifikatorlar
	IUPAC nomi (RS) -1 - [(2-Metil-1H-indol-4-yl) oksi] -3- (propan-2-ilamino) propan-2-ol;
CAS raqami	23694-81-7;
PubChem CID	71698;
ChemSpider	64750;
UNII	00Q31ER368;
KEGG	D07181;
ECHA ma'lumot kartasi	100.041.650
Kimyoviy va fizik ma'lumotlar
Formula	C15H22N2O2
Molyar massa	262.353 g · mol−1
3D model (JSmol)	Interaktiv rasm;
Chirallik	Rasemik aralashmasi
	Jilmayganlar CC1 = CC2 = C (N1) C = CC = C2OCC (CNC (C) C) O;
	InChI InChI = 1S / C15H22N2O2 / c1-10 (2) 16-8-12 (18) 9-19-15-6-4-5-14-13 (15) 7-11 (3) 17-14 / h4- 7,10,12,16-18H, 8-9H2,1-3H3; Kalit: NXWGWUVGUSFQJC-UHFFFAOYSA-N;

Mepindolol

Mepindolol (Betagon) tanlanmagan beta bloker. U davolash uchun ishlatiladi glaukoma.^[1]

Shuningdek qarang

Pindolol

Adabiyotlar

^ Schmid MG, Gecse O, Szabo Z, Kilar F, Gübitz G, Ali I, Aboul-Enein HY (sentyabr 2001). "B-blokerlarning tsellyuloza tris (3,5-dimetil-fenilkarbamat) fazalaridagi chiral rezolyutsiyasini normal va teskari o'zgarishlar rejimida qiyosiy o'rganish". Suyuq xromatografiya va tegishli texnologiyalar jurnali. 24 (16): 2493–2504. doi:10.1081 / JLC-100105955.

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[1] Schmid MG, Gecse O, Szabo Z, Kilar F, Gübitz G, Ali I, Aboul-Enein HY (sentyabr 2001). "B-blokerlarning tsellyuloza tris (3,5-dimetil-fenilkarbamat) fazalaridagi chiral rezolyutsiyasini normal va teskari o'zgarishlar rejimida qiyosiy o'rganish". Suyuq xromatografiya va tegishli texnologiyalar jurnali. 24 (16): 2493–2504. doi:10.1081 / JLC-100105955.

[1]

v t e Beta blokerlar (C07)
β, tanlanmagan	Alprenolol Bopindolol Bupranolol Karteolol Kloranol Mepindolol Nadolol Oksprenolol Penbutolol Pindolol/Iodopindolol Propranolol^# Sotalol Tertatolol Timolol^#
β₁-selektiv	Asebutolol Atenolol Betaxolol Bevantolol Bisoprolol^# Celiprolol Epanolol Esmolol Landiolol Metoprolol Nebivolol Practolol Talinolol
β₂-selektiv	Butaksamin
a₁- + β-selektiv	Arotinolol Carvedilol Labetalol
^#JSST-EM ^‡Olingan bozordan Klinik sinovlar: ^†III bosqich ^§Hech qachon III bosqichga

v t e Adrenergik retseptorlari modulyatorlar
a₁	Agonistlar: 6-FNE Amidefrin Anizodin Buspirone Sirazolin Korbadrin Desglimidodrin Deksizometeptene Dipivefrin Dopamin Droksidopa (L-DOPS) Efedrin Epinefrin Etilefrin Etilevodopa Etilnorepinefrin Indanidin Izometheptene L-DOPA (levodopa) L-Fenilalanin L-Tirozin Melevodopa Metaraminol Metoksamin Metildopa Midodrin Nafazolin Norepinefrin Ahtapamin Oksimetazolin Fenilefrin Fenilpropanolamin Psödoefedrin Sinefrin Tetrizolin Tiamenidin XP21279 Ksilometazolin Antagonistlar: Abanquil Adimolol Ajmalitsin Alfuzosin Amosulalol Anizodamin Arotinolol Atiprosin Atipik antipsikotiklar (masalan, brekspiprazol, klozapin, olanzapin, ketiapin, risperidon) Benoksatian Buflomedil Bunazosin Carvedilol Korynantin Dapiprazol Mahalliy Doksazosin Ergolines (masalan, ergotamin, dihidroergotamin, lisurid, tergurid) Etoperidon Evgenodilol Fenspirid Gidroksizin Indoramin Ketanserin L-765,314 Labetalol mCPP Mepiprazol Metazosin Monatepil Moksisilit Naftopidil Nantenin Neldazosin Niaprazin Nikergolin Niguldipine Pardoprunoks Pelanserin Perlapin Phendioxan Fenoksibenzamin Fentolamin Fenilpiperazin antidepressantlar (masalan, gidroksifazodon, nefazodon, trazodon, triazoledion) Piperoksan Prazosin Kinazosin Kinidin Ritanserin Silodosin Spiperon Talipeksol Tamsulosin Terazosin Tiodazosin Tolazolin Tetratsiklik antidepressantlar (masalan, amoksapin, maprotilin, mianserin) Trisiklik antidepressantlar (masalan, amitriptilin, klomipramin, doksepin, imipramin, trimipramin) Trimazosin Odatda antipsikotiklar (masalan, xlorpromazin, flüfenazin, loxapin, tioridazin) Urapidil WB-4101 Zolertin
a₂	Agonistlar: (R) -3-nitrobifenilin 4-NEMD 6-FNE Amitraz Apraklonidin Brimonidin Kannabivarin Klonidin Korbadrin Detomidin Deksmedetomidin Dihidroergotamin Dipivefrin Dopamin Droksidopa (L-DOPS) Etilevodopa Efedrin Ergotamin Epinefrin Etilefrin Etilnorepinefrin Guanabenz Guanfasin Guanoksabenz L-DOPA (levodopa) L-Fenilalanin L-Tirozin Lofexidin Medetomidin Melevodopa Metildopa Mivazerol Nafazolin Norepinefrin Oksimetazolin Fenilpropanolamin Piperoksan Psödoefedrin Rezatomidin Rilmenidin Romifidin Talipeksol Tasipimidin Tetrahidrozolin Tiamenidin Tizanidin Tolonidin Urapidil Vatinoksan XP21279 Ksilazin Ksilometazolin Antagonistlar: 1-PP Adimolol Amesergid Aptazapin Atipamezol Atipik antipsikotiklar (masalan, asenapin, brekspiprazol, klozapin, lurasidon, olanzapin, paliperidon, ketiapin, risperidon, zotepin) Azapironlar (masalan, buspirone, gepiron, ipsapirone, tandospiron) BRL-44408 Buflomedil Sirazolin Efaroksan Esmirtazapin Fenmetozol Fluparoksan Idazoksan mCPP Mianserin Mirtazapin NAN-190 Pardoprunoks Fentolamin Fenoksibenzamin Piperoksan Piribedil Rawolscine Rotigotin SB-269970 Setiptiline Spiroksatrin Sunepitron Tolazolin Odatda antipsikotiklar (masalan, xlorpromazin, flüfenazin, loxapin, tioridazin) Yohimbine
β	Agonistlar: Abediterol Alifedrin Amibegron Arbutamin Arformoterol Arotinolol BAAM Bambuterol Befunolol Bitolterol Broksaterol Bupenin Karbuterol Karmoterol Cimaterol Klenbuterol Kolterol Korbadrin Denopamin Dipivefrin Dobutamin Dopamin Dopeksamin Droksidopa (L-DOPS) Efedrin Epinefrin Etafedrin Etilefrin Etilevodopa Etilnorepinefrin Fenoterol Formoterol Geksoprenalin Higenamin Indakaterol Isoetarin Izoprenalin Isoxsuprin L-DOPA (levodopa) L-Fenilalanin L-Tirozin Levosalbutamol Mabuterol Melevodopa Metoksifenamin Metildopa Mirabegron Norepinefrin Orsiprenalin Oksifedrin PF-610355 Fenilpropanolamin Pirbuterol Prenalterol Raktopamin Prokaterol Psödoefedrin Reproterol Rimiterol Ritodrin Salbutamol Salmeterol Solabegron Terbutalin Tretoxinol Tulobuterol Vilanterol Xamoterol XP21279 Zilpaterol Zinterol Antagonistlar: Asebutolol Adaprolol Adimolol Afurolol Alprenolol Alprenoksim Amosulalol Ancarolol Arnolol Arotinolol Atenolol Befunolol Betaxolol Bevantolol Bisoprolol Bopindolol Bornaprolol Brefonalol Bucindolol Bucumolol Bufetolol Bufuralol Bunitrolol Bunolol Bupranolol Butaksamin Butidrin Butofilolol Kapsinolol Karazolol Karpindolol Karteolol Carvedilol Celiprolol Setamolol Tsikloprolol Cinamolol Kloranol Siyanopindolol Dalbraminol Dexpropranolol Diatsetolol Dikloroizoprenalin Dihidroalprenolol Dilevalol Diprafenon Drakinolol Ecastolol Epanolol Erikolol Ersentilid Esatenolol Esprolol Evgenodilol Exaprolol Falintolol Flestolol Flusoksolol Gidroksikarteolol Gidroksistertolol ICI-118,551 Idropranolol Indenolol Indopanolol Iodosiyanopindolol Iprokrolol Isoxaprolol Isamoltan Labetalol Landiolol Levobetaxolol Levobunolol Levomoprolol Medroxalol Mepindolol Metipranolol Metoprolol Moprolol Nadolol Nadoksolol Nebivolol Nifenalol Nipradilol Oksprenolol Pakrinolol Pafenolol Pamatolol Pargolol Penbutolol Pindolol Practolol Primidolol Protsinolol Pronetalol Propafenon Propranolol Ridazolol Ronaktolol Soquinolol Sotalol Spirendolol SR 59230A Sulfinalol Talinolol Tazolol Tertatolol Tienoksolol Tilisolol Timolol Tiprenolol Tolamolol Toliprolol Xibenolol Xipranolol
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Klinik ma'lumotlar

ATC kodi	C07AA14 (JSSV)
Identifikatorlar
IUPAC nomi (RS) -1 - [(2-Metil-1H-indol-4-yl) oksi] -3- (propan-2-ilamino) propan-2-ol
CAS raqami	23694-81-7
PubChem CID	71698
ChemSpider	64750
UNII	00Q31ER368
KEGG	D07181
ECHA ma'lumot kartasi	100.041.650
Kimyoviy va fizik ma'lumotlar
Formula	C₁₅H₂₂N₂O₂
Molyar massa	262.353 g · mol⁻¹
3D model (JSmol)	Interaktiv rasm
Chirallik	Rasemik aralashmasi
Jilmayganlar CC1 = CC2 = C (N1) C = CC = C2OCC (CNC (C) C) O
InChI InChI = 1S / C15H22N2O2 / c1-10 (2) 16-8-12 (18) 9-19-15-6-4-5-14-13 (15) 7-11 (3) 17-14 / h4- 7,10,12,16-18H, 8-9H2,1-3H3 Kalit: NXWGWUVGUSFQJC-UHFFFAOYSA-N