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Minamestan
Klinik ma'lumotlar
ATC kodi	Yo'q;
Identifikatorlar
	IUPAC nomi 4-aminoandrosta-1,4,6-trien-3,17-dion;
CAS raqami	105051-87-4;
PubChem CID	65886;
ChemSpider	59295;
UNII	J02058ABVE;
CompTox boshqaruv paneli (EPA)	DTXSID40883152 ;
Kimyoviy va fizik ma'lumotlar
Formula	C19H23NO2
Molyar massa	297.398 g · mol−1
3D model (JSmol)	Interaktiv rasm;
	Jilmayganlar O = C4 C = C / [C @] 3 (C (/ C = C [C @ H] 2 [C @ H] 1 [C @@] (C (= O) CC1)) (CC [C @@ H] 23) C) = C4 / N) C;
	InChI InChI = 1S / C19H23NO2 / c1-18-10-8-15 (21) 17 (20) 14 (18) 4-3-11-12-5-6-16 (22) 19 (12,2) 9- 7-13 (11) 18 / h3-4,8,10-13H, 5-7,9,20H2,1-2H3 / t11-, 12-, 13-, 18 +, 19- / m0 / s1; Kalit: DAKHYLIFCYPHQW-KZQROQTASA-N;

Minamestane

Minamestan (KARVONSAROY (avvalgi rivojlanish kodining nomi FCE-24,928) a steroidal aromataza inhibitori tomonidan ishlab chiqilgan Farmitalia-Karlo Erba sifatida antineoplastik vosita 1990-yillarning o'rtalarida, lekin hech qachon sotilmadi.^[1]^[2]^[3]

Kabi boshqa steroidal aromataz inhibitörlerinden farqli o'laroq formestan va exemestane, minamestanda yo'q androgenik xususiyatlari.^[2]

Shuningdek qarang

^ F .. Makdonald (1997). Farmakologik agentliklar lug'ati. CRC Press. p. 1357. ISBN 978-0-412-46630-4. Olingan 20 may 2012.
^ ^a ^b Di Salle E, Briatiko G, Giudici D va boshq. (Iyun 1994). "Yangi aromataza va 5 alfa-reduktaza inhibitori". Steroid biokimyosi va molekulyar biologiya jurnali. 49 (4–6): 289–94. doi:10.1016/0960-0760(94)90270-4. PMID 8043491. S2CID 54350143.
^ Taraklar, Donald V (1995). "Onkologik, endokrin va metabolik tekshiruv: aromataza inhibitörlerinin so'nggi rivojlanishi". Terapevtik patentlar bo'yicha mutaxassislarning fikri. 5 (6): 529533. doi:10.1517/13543776.5.6.529. ISSN 1354-3776.

Bu antineoplastik yoki immunomodulyatsion dori maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

Klinik ma'lumotlar

ATC kodi	Yo'q
Identifikatorlar
IUPAC nomi 4-aminoandrosta-1,4,6-trien-3,17-dion
CAS raqami	105051-87-4
PubChem CID	65886
ChemSpider	59295
UNII	J02058ABVE
CompTox boshqaruv paneli (EPA)	DTXSID40883152
Kimyoviy va fizik ma'lumotlar
Formula	C₁₉H₂₃NO₂
Molyar massa	297.398 g · mol⁻¹
3D model (JSmol)	Interaktiv rasm
Jilmayganlar O = C4 C = C / [C @] 3 (C (/ C = C [C @ H] 2 [C @ H] 1 [C @@] (C (= O) CC1)) (CC [C @@ H] 23) C) = C4 / N) C
InChI InChI = 1S / C19H23NO2 / c1-18-10-8-15 (21) 17 (20) 14 (18) 4-3-11-12-5-6-16 (22) 19 (12,2) 9- 7-13 (11) 18 / h3-4,8,10-13H, 5-7,9,20H2,1-2H3 / t11-, 12-, 13-, 18 +, 19- / m0 / s1 Kalit: DAKHYLIFCYPHQW-KZQROQTASA-N