WikiDer > Nepidermin

Nepidermin
Klinik ma'lumotlar
Savdo nomlari	Easyef, Genesoft, Kang He Su, Regen-D
Boshqa ismlar	Rekombinant odamning epidermal o'sish omili; rhEGF; DWP-401
Marshrutlari; ma'muriyat	Mavzuga oid
Identifikatorlar
	IUPAC nomi H-Asn-Ser-Asp-Ser-Glu-Cys-Pro-Leu-Ser-His-Asp-Gly-Tyr-Cys-Leu-His-Asp-Gly-Val-Cys-Met-Tyr-Ile-Glu- Ala-Leu-Asp-Lys-Tyr-Ala-Cys-Asn-Cys-Val-Val-Gly-Tyr-Ile-Gly-Glu-Arg-Cys-Gln-Tyr-Arg-Asp-Leu-Lys-Trp- Trp-Glu-Leu-Arg-OH;
CAS raqami	62253-63-8;
PubChem CID	16143379;
ChemSpider	17299876;
UNII	TZK30RF92W;
CompTox boshqaruv paneli (EPA)	DTXSID80211314 ;
ECHA ma'lumot kartasi	100.241.060
Kimyoviy va fizik ma'lumotlar
Formula	C270H401N73O83S7
Molyar massa	6222.03 g · mol−1
3D model (JSmol)	Interaktiv rasm;
	Jilmayganlar CC [C @ H] (C) [C @@ H] (C (= O) NCC (= O) N [C @@ H] (CCC (= O) O) C (= O) N [C @ @H] (CCCNC (= N) N) C (= O) N [C @@ H] (CS) C (= O) N [C @@ H] (CCC (= O) N) C (= O ) N [C @@ H] (CC1 = CC = C (C = C1) O) C (= O) N [C @@ H] (CCCNC (= N) N) C (= O) N [C @ @H] (CC (= O) O) C (= O) N [C @@ H] (CC (C) C) C (= O) N [C @@ H] (CCCCN) C (= O) N [C @@ H] (CC2 = CNC3 = CC = CC = C32) C (= O) N [C @@ H] (CC4 = CNC5 = CC = CC = C54) C (= O) N [C @ @H] (CCC (= O) O) C (= O) N [C @@ H] (CC (C) C) C (= O) N [C @@ H] (CCCNC (= N) N) C (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC6 = CC = C (C = C6) O) bosimining ko'tarilishi (= O) CNC (= O) [C @ H] (C (C) C) bosimining ko'tarilishi (= O) [C @ H] (C (C) C) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) N) Bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (C) bosimining ko'tarilishi (= O) [C @ H] (CC7 = CC = C (C = C7) O) bosimining ko'tarilishi (= O) [C @ H] (CCCCN) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC (C) C) bosimining ko'tarilishi (= O) [C @ H] (C) NC (= O) [C @ H] (CCC (= O) O) NC (= O) [C @ H] ([C @@ H] (C) CC) Bosimining ko'tarilishi (= O) [C @ H] (CC8 = CC = C (C = C8) O) bosimining ko'tarilishi (= O) [C @ H] (CCSC) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (C (C) C) NC (= O) CNC (= O) [C @ H] (CC (= O) O) NC (= O) [C @ H] ( CC9 = CN = CN9) bosimining ko'tarilishi (= O) [C @ H] (CC (C) C) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CC1 = CC = C (C = C1) O) bosimining ko'tarilishi (= O) CNC (= O) [C @ H] (CC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC1 = CN = CN1) bosimining ko'tarilishi (= O) [C @ H] (CO) NC (= O) [C @ H] (CC (C) C) NC (= O) [C @@ H] 1CCCN1C (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CCC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CO) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) O) N C (= O) [C @ H] (CO) NC (= O) [C @ H] (CC (= O) N) N;
	InChI InChI = 1S / C270H401N73O83S7 / c1-24-134 (19) 217 (262 (420) 293-112-201 (355) 298-161 (69-74-205 (359) 360) 229 (387) 301-160) 45-35-82-286-269 (279) 280) 228 (386) 333-192 (119-428) 255 (413) 307-162 (68-73-198 (274) 352) 230 (388) 316- 176 (94-141-54-64-150 (350) 65-55-141) 241 (399) 304-159 (44-34-81-285-268 (277) 278) 227 (385) 325-186 ( 105-212 (373) 374) 248 (406) 313-169 (87-127 (5) 6) 235 (393) 302-158 (43-31-33-80-272) 226 (384) 318-179 ( 97-144-108-289-156-41-29-27-39-153 (144) 156) 243 (401) 319-178 (96-143-107-288-155-40-28-26-38-) 152 (143) 155) 242 (400) 305-164 (71-76-207 (363) 364) 231 (389) 312-170 (88-128 (7) 8) 236 (394) 310-167 (267 () 425) 426) 46-36-83-287-270 (281) 282) 341-250 (408) 174 (92-139-50-60-148 (348) 61-51-139) 300-203 (357) 113-292-261 (419) 214 (131 (13) 14) 340-264 (422) 216 (133 (17) 18) 339-259 (417) 195 (122-431) 335-246 (404) 182 ( 101-200 (276) 354) 322-257 (415) 191 (118-427) 332-220 (378) 137 (22) 297-234 (392) 175 (93-140-52-62-149 (349)) 63-53-140) 315-225 (383) 157 (42-30-32-79-271) 303-247 (405) 185 (104-211 (371) 372) 326-237 (395) 168 (86-) 126 (3) 4) 311-219 (377) 136 (21) 296-224 (382) 163 (70-75-206 ( 361) 362) 309-265 (423) 218 (135 (20) 25-2) 342-251 (409) 177 (95-142-56-66-151 (351) 67-57-142) 317-233 ( 391) 166 (78-85-433-23) 308-256 (414) 194 (121-430) 336-263 (421) 215 (132 (15) 16) 338-204 (358) 114-291-223 () 381) 184 (103-210 (369) 370) 323-244 (402) 180 (98-145-109-283-124-294-145) 320-238 (396) 171 (89-129 (9) 10) 314-258 (416) 193 (120-429) 334-240 (398) 173 (91-138-48-58-147 (347) 59-49-138) 299-202 (356) 111-290-222 ( 380) 183 (102-209 (367) 368) 324-245 (403) 181 (99-146-110-284-125-295-146) 321-254 (412) 190 (117-346) 330-239 ( 397) 172 (90-130 (11) 12) 328-260 (418) 197-47-37-84-343 (197) 266 (424) 196 (123-432) 337-232 (390) 165 (72-) 77-208 (365) 366) 306-252 (410) 189 (116-345) 331-249 (407) 187 (106-213 (375) 376) 327-253 (411) 188 (115-344) 329- 221 (379) 154 (273) 100-199 (275) 353 / h26-29,38-41,48-67,107-110,124-137,154,157-197,214-218,288-289,344-351,427-432H, 24-25,30-37, 42-47,68-106,111-123,271-273H2,1-23H3, (H2,274,352) (H2,275,353) (H2,276,354) (H, 283,294) (H, 284,295) (H, 290,380) (H, 291,381) ) (H, 292,419) (H, 293,420) (H, 296,382) (H, 297,392) (H, 298,355) (H, 299,356) (H, 300,357) (H, 301,387) (H, 302,393) (H, 303,405) (H, 304,399) (H, 305,400) (H, 306,410) (H, 307,413) (H, 308,414) (H, 309,423) (H, 310,394) (H, 311,377) (H, 312,389) (H, 313,406) (H, 314,416) (H, 315,383) (H, 316,388) (H, 317,391) (H, 318,384) (H, 319,401) (H, 320,396) (H, 321,412) (H, 322,415) (H, 323,402) (H, 324,403) (H, 325,385) (H, 326,395) (H, 327,411) (H, 328,418) (H, 329,379) (H, 330,397) (H, 331,407) (H, 332,378) (H, 333,386) (H, 334,398) (H, 335,404) (H, 336,421) (H, 337,390) (H, 338,358) (H, 339,417) (H, 340,422) (H, 341,408) (H, 342,409) (H, 359,360) (H, 361,362) (H, 363,364) (H, 365,366) (H, 367,368) (H, 369,370) (H, 371,372) (H, 373,374) (H, 375,376) (H, 425,426) (H4,277,278,285) (H4,279,280,286) (H4,281,282,287) / t134-, 135-, 136-, 137-, 154-, 157-, 158-, 159-, 160-, 161-, 162- , 163-, 164-, 165-, 166-, 167-, 168-, 169-, 170-, 171-, 172-, 173-, 174-, 175-, 176-, 177-, 178-, 179 -, 180-, 181-, 182-, 183-, 184-, 185-, 186-, 187-, 188-, 189-, 190-, 191-, 192-, 193-, 194-, 195-, 196-, 197-, 214-, 215-, 216-, 217-, 218- / m0 / s1; Kalit: GVUGOAYIVIDWIO-UFWWTJHBSA-N;

Nepidermin

Nepidermin (brendning nomi Easyef), shuningdek, nomi bilan tanilgan rekombinant odamning epidermal o'sish omili (rhEGF), a rekombinant shakli inson epidermal o'sish omili (EGF) va a tsikratrizant (chandiq to'qimasini hosil qilish orqali jarohatni davolashga yordam beradigan dori). U tomonidan ishlab chiqilgan Daewoong farmatsevtika.^[1]^[2]^[3] EGFning rekombinant shakli sifatida nepidermin - ning agonisti epidermal o'sish omil retseptorlari (EGFR) va sotiladigan birinchi EGFR agonisti.^[2]^[3]

An sifatida sotiladi malham davolash uchun diabetik oyoq yaralari, yaralarva alopesiya (soch to'kilishi) in Vetnam, Filippinlar, Tailandva Xitoy.^[1]^[2]^[3]

2017 yildan boshlab Janubiy Koreyada davolanish uchun klinik sinovlarda bo'lgan stomatit (og'iz yoki labning yallig'lanishi) va terining yon ta'sirini qaytarish uchun erlotinib (an EGFR inhibitori).^[2]^[4]

Shuningdek qarang

Adabiyotlar

^ ^a ^b ^v "Nepidermin". Drugs.com. Olingan 3 iyun 2017.
^ ^a ^b ^v ^d "Nepidermin". AdisInsight. Olingan 3 iyun 2017.
^ ^a ^b ^v Lau, Xuy-Chong; Kim, Aeri (2016). "Oyoqning diabetik yarasida yarani davolashni buzilishining farmatsevtika istiqbollari". Farmatsevtika tekshiruvi jurnali. 46 (5): 403–423. doi:10.1007 / s40005-016-0268-6. ISSN 2093-5552.
^ Yuan A, Sonis S (2014). "Og'iz mukozitining oldini olish va davolash uchun paydo bo'ladigan terapiya". Mutaxassis Opin paydo bo'lgan giyohvand moddalar. 19 (3): 343–51. doi:10.1517/14728214.2014.946403. PMID 25102771.

Bu oqsilbilan bog'liq maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

Bu dermatologik dori maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[Drugs.com-1] v "Nepidermin". Drugs.com. Olingan 3 iyun 2017.

[AdisInsight-2] v ^d "Nepidermin". AdisInsight. Olingan 3 iyun 2017.

[LauKim2016-3] v Lau, Xuy-Chong; Kim, Aeri (2016). "Oyoqning diabetik yarasida yarani davolashni buzilishining farmatsevtika istiqbollari". Farmatsevtika tekshiruvi jurnali. 46 (5): 403–423. doi:10.1007 / s40005-016-0268-6. ISSN 2093-5552.

[pmid25102771-4] Yuan A, Sonis S (2014). "Og'iz mukozitining oldini olish va davolash uchun paydo bo'ladigan terapiya". Mutaxassis Opin paydo bo'lgan giyohvand moddalar. 19 (3): 343–51. doi:10.1517/14728214.2014.946403. PMID 25102771.

[1]

[2]

[3]

[4]

v t e Davolashga tayyorgarlik yaralar va oshqozon yarasi (D03)
Tsikratrizantlar	epiklorohidrin: Kadeksomer yod Krilanomer Dekstranomer B5: Kaltsiy pantotenat Dexpantenol nitrat: Nitrogliserin Izosorbid dinitrat boshqa: Bekaplermin Enoksolon Gialuron kislotasi Nepidermin Trafermin
Proteolitik fermentlar	Bromelain Klostridiopeptidaza Tripsin

v t e Boshqalar dermatologik tayyorgarlik (D11)
Seboreikaga qarshi vositalar	Antiandrogenlar Bikalutamid Siproteron asetat Flutamid Spironolakton Qo'ziqorinlarga qarshi vositalar Bifonazol Cetrimonium bromid (ketrimid) Siklopiroks olamin (siklopiroks) Klimbazol Klotrimazol Ketokonazol Mikonazol Pirokton olamin Seleniy disulfid (selen sulfidi) Ksenisalat Sink pirition (pirition rux) Antihistaminiklar Kalsineurin inhibitörleri Siklosporin Pimekrolimus Takrolimus Izotretinoin Keratolitiklar Ko'mir smolasi Resortsinol Salitsil kislotasi Oltingugurt Karbamid (karbamid o'z ichiga olgan krem) Lityum tuzlari Lityum glyukonat Lityum süksinat Mahalliy kortikosteroidlar (masalan, gidrokortizon)
Terini yoritish	Gidrokinon Mexinol Monobenzon
Teri qorayadi	Afamelanotid Melanotan II
Yallig'lanishga qarshi vositalar	Oksatseprol Gamolen kislotasi Pimekrolimus Takrolimus Alitretinoin Mahalliy kortikosteroidlar (masalan, gidrokortizon)
Alopesiyani davolash	5a-Reduktaza inhibitörleri Alfatradiol Dutasterid Finasterid Palmetto ekstraktini ko'rdim Antiandrogenlar Bikalutamid Siproteron asetat Flutamid Spironolakton Topilutamid (fluridil) Kaliy kanal ochgichlari Minoksidil Boshqalar Nepidermin
Soch o'sishi inhibitörleri	5a-Reduktaza inhibitörleri Dutasterid Finasterid Antiandrogenlar Bikalutamid Siproteron asetat Flutamid Spironolakton Eflornitin
Boshqalar	Androgenlar (masalan, testosteron) Brimonidin Kaltsiy glyukonat Estrogenlar (masalan, estradiol) Gialuron kislotasi Magnezium sulfat Pregnenolon asetat Progestogenlar (masalan, progesteron) Povidon-yod Tiratricol

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WikiDer > Nepidermin

Shuningdek qarang

Adabiyotlar

Klinik ma'lumotlar
Savdo nomlari	Easyef, Genesoft, Kang He Su, Regen-D^[1]
Boshqa ismlar	Rekombinant odamning epidermal o'sish omili; rhEGF; DWP-401
Marshrutlari ma'muriyat	Mavzuga oid
Identifikatorlar
IUPAC nomi H-Asn-Ser-Asp-Ser-Glu-Cys-Pro-Leu-Ser-His-Asp-Gly-Tyr-Cys-Leu-His-Asp-Gly-Val-Cys-Met-Tyr-Ile-Glu- Ala-Leu-Asp-Lys-Tyr-Ala-Cys-Asn-Cys-Val-Val-Gly-Tyr-Ile-Gly-Glu-Arg-Cys-Gln-Tyr-Arg-Asp-Leu-Lys-Trp- Trp-Glu-Leu-Arg-OH
CAS raqami	62253-63-8
PubChem CID	16143379
ChemSpider	17299876
UNII	TZK30RF92W
CompTox boshqaruv paneli (EPA)	DTXSID80211314
ECHA ma'lumot kartasi	100.241.060
Kimyoviy va fizik ma'lumotlar
Formula	C₂₇₀H₄₀₁N₇₃O₈₃S₇
Molyar massa	6222.03 g · mol⁻¹
3D model (JSmol)	Interaktiv rasm
Jilmayganlar CC [C @ H] (C) [C @@ H] (C (= O) NCC (= O) N [C @@ H] (CCC (= O) O) C (= O) N [C @ @H] (CCCNC (= N) N) C (= O) N [C @@ H] (CS) C (= O) N [C @@ H] (CCC (= O) N) C (= O ) N [C @@ H] (CC1 = CC = C (C = C1) O) C (= O) N [C @@ H] (CCCNC (= N) N) C (= O) N [C @ @H] (CC (= O) O) C (= O) N [C @@ H] (CC (C) C) C (= O) N [C @@ H] (CCCCN) C (= O) N [C @@ H] (CC2 = CNC3 = CC = CC = C32) C (= O) N [C @@ H] (CC4 = CNC5 = CC = CC = C54) C (= O) N [C @ @H] (CCC (= O) O) C (= O) N [C @@ H] (CC (C) C) C (= O) N [C @@ H] (CCCNC (= N) N) C (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC6 = CC = C (C = C6) O) bosimining ko'tarilishi (= O) CNC (= O) [C @ H] (C (C) C) bosimining ko'tarilishi (= O) [C @ H] (C (C) C) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) N) Bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (C) bosimining ko'tarilishi (= O) [C @ H] (CC7 = CC = C (C = C7) O) bosimining ko'tarilishi (= O) [C @ H] (CCCCN) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC (C) C) bosimining ko'tarilishi (= O) [C @ H] (C) NC (= O) [C @ H] (CCC (= O) O) NC (= O) [C @ H] ([C @@ H] (C) CC) Bosimining ko'tarilishi (= O) [C @ H] (CC8 = CC = C (C = C8) O) bosimining ko'tarilishi (= O) [C @ H] (CCSC) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (C (C) C) NC (= O) CNC (= O) [C @ H] (CC (= O) O) NC (= O) [C @ H] ( CC9 = CN = CN9) bosimining ko'tarilishi (= O) [C @ H] (CC (C) C) bosimining ko'tarilishi (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CC1 = CC = C (C = C1) O) bosimining ko'tarilishi (= O) CNC (= O) [C @ H] (CC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CC1 = CN = CN1) bosimining ko'tarilishi (= O) [C @ H] (CO) NC (= O) [C @ H] (CC (C) C) NC (= O) [C @@ H] 1CCCN1C (= O) [C @ H] (CS) bosimining ko'tarilishi (= O) [C @ H] (CCC (= O) O) bosimining ko'tarilishi (= O) [C @ H] (CO) bosimining ko'tarilishi (= O) [C @ H] (CC (= O) O) N C (= O) [C @ H] (CO) NC (= O) [C @ H] (CC (= O) N) N
InChI InChI = 1S / C270H401N73O83S7 / c1-24-134 (19) 217 (262 (420) 293-112-201 (355) 298-161 (69-74-205 (359) 360) 229 (387) 301-160) 45-35-82-286-269 (279) 280) 228 (386) 333-192 (119-428) 255 (413) 307-162 (68-73-198 (274) 352) 230 (388) 316- 176 (94-141-54-64-150 (350) 65-55-141) 241 (399) 304-159 (44-34-81-285-268 (277) 278) 227 (385) 325-186 ( 105-212 (373) 374) 248 (406) 313-169 (87-127 (5) 6) 235 (393) 302-158 (43-31-33-80-272) 226 (384) 318-179 ( 97-144-108-289-156-41-29-27-39-153 (144) 156) 243 (401) 319-178 (96-143-107-288-155-40-28-26-38-) 152 (143) 155) 242 (400) 305-164 (71-76-207 (363) 364) 231 (389) 312-170 (88-128 (7) 8) 236 (394) 310-167 (267 () 425) 426) 46-36-83-287-270 (281) 282) 341-250 (408) 174 (92-139-50-60-148 (348) 61-51-139) 300-203 (357) 113-292-261 (419) 214 (131 (13) 14) 340-264 (422) 216 (133 (17) 18) 339-259 (417) 195 (122-431) 335-246 (404) 182 ( 101-200 (276) 354) 322-257 (415) 191 (118-427) 332-220 (378) 137 (22) 297-234 (392) 175 (93-140-52-62-149 (349)) 63-53-140) 315-225 (383) 157 (42-30-32-79-271) 303-247 (405) 185 (104-211 (371) 372) 326-237 (395) 168 (86-) 126 (3) 4) 311-219 (377) 136 (21) 296-224 (382) 163 (70-75-206 ( 361) 362) 309-265 (423) 218 (135 (20) 25-2) 342-251 (409) 177 (95-142-56-66-151 (351) 67-57-142) 317-233 ( 391) 166 (78-85-433-23) 308-256 (414) 194 (121-430) 336-263 (421) 215 (132 (15) 16) 338-204 (358) 114-291-223 () 381) 184 (103-210 (369) 370) 323-244 (402) 180 (98-145-109-283-124-294-145) 320-238 (396) 171 (89-129 (9) 10) 314-258 (416) 193 (120-429) 334-240 (398) 173 (91-138-48-58-147 (347) 59-49-138) 299-202 (356) 111-290-222 ( 380) 183 (102-209 (367) 368) 324-245 (403) 181 (99-146-110-284-125-295-146) 321-254 (412) 190 (117-346) 330-239 ( 397) 172 (90-130 (11) 12) 328-260 (418) 197-47-37-84-343 (197) 266 (424) 196 (123-432) 337-232 (390) 165 (72-) 77-208 (365) 366) 306-252 (410) 189 (116-345) 331-249 (407) 187 (106-213 (375) 376) 327-253 (411) 188 (115-344) 329- 221 (379) 154 (273) 100-199 (275) 353 / h26-29,38-41,48-67,107-110,124-137,154,157-197,214-218,288-289,344-351,427-432H, 24-25,30-37, 42-47,68-106,111-123,271-273H2,1-23H3, (H2,274,352) (H2,275,353) (H2,276,354) (H, 283,294) (H, 284,295) (H, 290,380) (H, 291,381) ) (H, 292,419) (H, 293,420) (H, 296,382) (H, 297,392) (H, 298,355) (H, 299,356) (H, 300,357) (H, 301,387) (H, 302,393) (H, 303,405) (H, 304,399) (H, 305,400) (H, 306,410) (H, 307,413) (H, 308,414) (H, 309,423) (H, 310,394) (H, 311,377) (H, 312,389) (H, 313,406) (H, 314,416) (H, 315,383) (H, 316,388) (H, 317,391) (H, 318,384) (H, 319,401) (H, 320,396) (H, 321,412) (H, 322,415) (H, 323,402) (H, 324,403) (H, 325,385) (H, 326,395) (H, 327,411) (H, 328,418) (H, 329,379) (H, 330,397) (H, 331,407) (H, 332,378) (H, 333,386) (H, 334,398) (H, 335,404) (H, 336,421) (H, 337,390) (H, 338,358) (H, 339,417) (H, 340,422) (H, 341,408) (H, 342,409) (H, 359,360) (H, 361,362) (H, 363,364) (H, 365,366) (H, 367,368) (H, 369,370) (H, 371,372) (H, 373,374) (H, 375,376) (H, 425,426) (H4,277,278,285) (H4,279,280,286) (H4,281,282,287) / t134-, 135-, 136-, 137-, 154-, 157-, 158-, 159-, 160-, 161-, 162- , 163-, 164-, 165-, 166-, 167-, 168-, 169-, 170-, 171-, 172-, 173-, 174-, 175-, 176-, 177-, 178-, 179 -, 180-, 181-, 182-, 183-, 184-, 185-, 186-, 187-, 188-, 189-, 190-, 191-, 192-, 193-, 194-, 195-, 196-, 197-, 214-, 215-, 216-, 217-, 218- / m0 / s1 Kalit: GVUGOAYIVIDWIO-UFWWTJHBSA-N