WikiDer > Pirrobutamin

Pirrobutamin
Klinik ma'lumotlar
ATC kodi	R06AX08 (JSSV) ;
Identifikatorlar
	IUPAC nomi 1-[(2E) -4- (4-xlorofenil) -3-fenilbut-2-en-1-il] pirrolidin;
CAS raqami	91-82-7 ;
PubChem CID	5284614;
ChemSpider	4447659 ;
UNII	VE6KP18S8X;
ChEMBL	ChEMBL1697849 ;
CompTox boshqaruv paneli (EPA)	DTXSID9023544 ;
ECHA ma'lumot kartasi	100.001.911
Kimyoviy va fizik ma'lumotlar
Formula	C20H22ClN
Molyar massa	311.85 g · mol−1
3D model (JSmol)	Interaktiv rasm;
	Jilmayganlar C1CCN (C1) C / C = C (CC2 = CC = C (C = C2) Cl) / C3 = CC = CC = C3;
	InChI InChI = 1S / C20H22ClN / c21-20-10-8-17 (9-11-20) 16-19 (18-6-2-1-3-7-18) 12-15-22-13-4- 5-14-22 / h1-3,6-12H, 4-5,13-16H2 / b19-12 + ; Kalit: WDYYVNNRTDZKAZ-XDHOZWIPSA-N ;
	(bu nima?) (tasdiqlash)

Pyrrobutamine

Pirrobutamin bu antigistamin va antikolinerjik.^[1]

Adabiyotlar

^ Mothersill MH, Mills J, Li XM, Anderson RC, Harris PN (1953). "Antigistaminik birikma, pirrobutaminning kimyoviy va farmakologik xususiyatlari". Allergiya yilnomalari. 11 (6): 754–7. PMID 13114796.

Bu dori ga tegishli maqola nafas olish tizimi a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[1] Mothersill MH, Mills J, Li XM, Anderson RC, Harris PN (1953). "Antigistaminik birikma, pirrobutaminning kimyoviy va farmakologik xususiyatlari". Allergiya yilnomalari. 11 (6): 754–7. PMID 13114796.

[1]

v t e Antihistaminiklar (R06)
Benzimidazollar (*)	Astemizol Azelastin Bilastin Emedastin Mizolastin Talastin
Diarilmetanlar	Diarilmetoksialkilaminlar: Bromazin (bromodifenhidramin) Karbinoksamin Xlorfenoksamin Klemastin Difengidramin Difenilpiralin Doksilamin Ebastin Orfenadrin Difenilmetanolpiperidinlar: Feksofenadin Terfenadin Difenilmetilpiperazinlar: Buklizin Cetirizine Levotsetirizin Xlortsiklizin Sininarizin Siklizin Etodroksizin Gidroksizin Meklizin Oksatomid Fenilpiridinilpropanaminlar: Bromfeniramin Xlorfenamin Deksbromfeniramin (+ psevdoefedrin) Deksxlorfeniramin (+ betametazon) Feniramin Boshqalar: Akrivastin Bamipin Dimetindene Feniltoloksamin Pirrobutamin Quifenadin Triprolidin
Etilendiaminlar	Antazolin Xloropiramin Histapirrodin Mepiramin (pirilamin) Metapirilen Fenbenzamin Tenalidin Tripelennamin (piribenzamin)
Trisikliklar	Dibenzotsikloheptenlar: Antidepressantlar (masalan, amitriptilin) Azatadin Siproheptadin Deptropin Desloratadin Ketotifen Loratadin Rupatadin Fenotiyazinlar: Alimemazin Fenetazin Gidroksietilprometazin Izotipendil Mequitazin Metdilazin Oksomemazin Prometazin Boshqalar: Antidepressantlar (masalan, doksepin, mirtazapin, trimipramin) Epinastin Latrepirdin Mebhidrolin Olopatadin Perlapin Fenindamin Pimeteksen
Boshqalar	Fenilpiperazinlar: Antidepressantlar (masalan, trazodon) Fenbenzamin
Uchun dolzarb foydalanish	Bamipin Xloropiramin Xlorfenoksamin Klemastin Dimetindene Difengidramin Doksepin Izotipendil Mepiramin (pirilamin) Prometazin

v t e Gistamin retseptorlari modulyatorlar
H₁	Agonistlar: 2-piridiletilamin Betaxistin Gistamin HTMT L-Histidin UR-AK49 Antagonistlar: Birinchi avlod: 4-metildifenhidramin Alimemazin Antazolin Azatadin Bamipin Benzatropin (benztropin) Bepotastin Bromazin Bromfeniramin Buklizin Captodiame Karbinoksamin Xlortsiklizin Xloropiramin Xloroten Xlorfenamin Xlorfenoksamin Sininarizin Klemastin Klobenzepam Klocinizin Kloperastin Siklizin Siproheptadin Dacemazine Dekloksizin Deptropin Deksbromfeniramin Deksxlorfeniramin Dimenhidrinat Dimetindene Difengidramin Difenilpiralin Doksilamin Embramin Etodroksizin Etibenzatropin (etilbenztropin) Etimemazin Fenetazin Flunarizin Histapirrodin Gomoxlortsiklizin Gidroksietilprometazin Gidroksizin Izoprometazin Izotipendil Meklozin Medrilamin Mepiramin (pirilamin) Mequitazin Metafurilen Metapirilen Metdilazin Moksastin Orfenadrin Oksatomid Oksomemazin Perlapin Fenindamin Feniramin Feniltoloksamin Pimeteksen Piperoksan Pipoksizin Prometazin Propiomazin Pirrobutamin Talastin Tenalidin Tenildiamin Tiazinamium Tonzilamin Tolpropamin Tripelennamin Triprolidin Ikkinchi / uchinchi avlod: Akrivastin Alinastin Astemizol Azelastin Bamirastin Barmastin Bepiastin Bepotastin Bilastin Kabastinen Carebastine Cetirizine Klemastin Klemizol Klobenztropin Desloratadin Dorastin Ebastin Efletirizin Emedastin Epinastin Feksofenadin Flezelastin Ketotifen Latrepirdin Levokabastin Levotsetirizin Linetastin Loratadin Mapinastin Mebhidrolin Mizolastin Moksastin Noberastin Oktastin Olopatadin Perastin Pibaksizin Piklopastin Quifenadin (fenkarol) Rokastin Rupatadin Setastin Sekifenadin (bikarfen) Talastin Temelastin Terfenadin Vapitadin Zepastin Boshqalar: Atipik antipsikotiklar (masalan, aripiprazol, asenapin, brekspiprazol, brilaroksazin, klozapin, iloperidon, olanzapin, paliperidon, ketiapin, risperidon, ziprasidon, zotepin) Fenilpiperazin antidepressantlar (masalan, gidroksifazodon, nefazodon, trazodon, triazoledion) Tetratsiklik antidepressantlar (masalan, amoksapin, loxapin, maprotilin, mianserin, mirtazapin, oksaprotilin) Trisiklik antidepressantlar (masalan, amitriptilin, butriptilin, klomipramin, desipramin, dozulepin (dotiepin), doksepin, imipramin, iprindol, lofepramin, nortriptilin, protriptilin, trimipramin) Odatda antipsikotiklar (masalan, xlorpromazin, flupentiksol, flüfenazin, loxapin, perfenazin, proxlorperazin, tioridazin, tiyotiksen) Noma'lum / saralanmagan: Azanator Belorizin Elbanizin Flotrenizin GSK1004723 Napaktadin Tagorizin Trelnarizin Trenizin
H₂	Agonistlar: Amtamin Betazol Dimaprit Gistamin HTMT Impromidin L-Histidin UR-AK49 Antagonistlar: Bisfentidin Burimamid Simetidin Dalkotidin Donetidin Ebrotidin Etintidin Famotidin Izolamtidin Lafutidin Lamtidin Lavoltidin (loxtidin) Lupitidin Metiamid Mifentidin Niperotidin Nizatidin Osutidin Oksmetidin Pibutidin Quisultazine (quisultidine) Ramixotidin Ranitidin Roksatidin Sufotidin Tiotidin Tuvatidin Venritidin Xaltidin Zolantidin
H₃	Agonistlar: a-metilhistamin Kipralizant Gistamin Imetit Immepip Immetridin L-Histidin Methimepip Proksifan Antagonistlar: A-349821 A-423579 ABT-239 ABT-652 AZD5213 Bavisant Betaxistin Burimamid Siproksifan Klobenpropit Konessin Quvnoq GSK-189254 Impentamin Iodofenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Tioperamid VUF-5681
H₄	Agonistlar: 4-metilhistamin a-metilhistamin Gistamin L-Histidin OUP-16 VUF-8430 Antagonistlar: JNJ-7777120 Mianserin Seliforant Tioperamid Toreforant VUF-6002
Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari • Monoamin metabolizmining modulyatorlari • Monoaminni qaytarib olish inhibitörleri

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WikiDer > Pirrobutamin

Adabiyotlar

Klinik ma'lumotlar

ATC kodi	R06AX08 (JSSV)
Identifikatorlar
IUPAC nomi 1-[(2E) -4- (4-xlorofenil) -3-fenilbut-2-en-1-il] pirrolidin
CAS raqami	91-82-7^Y
PubChem CID	5284614
ChemSpider	4447659^N
UNII	VE6KP18S8X
ChEMBL	ChEMBL1697849^N
CompTox boshqaruv paneli (EPA)	DTXSID9023544
ECHA ma'lumot kartasi	100.001.911
Kimyoviy va fizik ma'lumotlar
Formula	C₂₀H₂₂ClN
Molyar massa	311.85 g · mol⁻¹
3D model (JSmol)	Interaktiv rasm
Jilmayganlar C1CCN (C1) C / C = C (CC2 = CC = C (C = C2) Cl) / C3 = CC = CC = C3
InChI InChI = 1S / C20H22ClN / c21-20-10-8-17 (9-11-20) 16-19 (18-6-2-1-3-7-18) 12-15-22-13-4- 5-14-22 / h1-3,6-12H, 4-5,13-16H2 / b19-12 +^N Kalit: WDYYVNNRTDZKAZ-XDHOZWIPSA-N^N
^NY (bu nima?) (tasdiqlash)