WikiDer > Talaporfin

Talaporfin
Klinik ma'lumotlar
AHFS/Drugs.com	Giyohvand moddalarning xalqaro nomlari
Marshrutlari; ma'muriyat	IV
ATC kodi	yo'q;
Huquqiy holat
Huquqiy holat	Umuman olganda: ℞ (faqat retsept bo'yicha);
Identifikatorlar
	IUPAC nomi N-{[(2S,3S) -7-karboksi-3- (2-karboksietil) -12-etil-2,8,13,18-tetrametil-17-vinil-2,3-dihidroporfirin-5-il] atsetil} -L-aspartik kislota;
CAS raqami	110230-98-3 ; 220201-34-3 (natriy tuzi);
PubChem CID	5486799;
ChemSpider	16737134 ;
UNII	P4ROX5ELT2;
Kimyoviy va fizik ma'lumotlar
Formula	C38H41N5O9
Molyar massa	711.772 g · mol−1
3D model (JSmol)	Interaktiv rasm;
	Jilmayganlar CCC1 = C2C = C3C (= C (C (= N3) C (= C4 [C @ H] ([C @@ H) (C (= N4) C = C5C (= C (C (= CC (= C1C) ) N2) N5) C = C) C) C) CCC (= O) O) CC (= O) N [C @@ H] (CC (= O) O) C (= O) O) C (=) O) O) C;
	InChI InChI = 1S / C38H41N5O9 / c1-7-20-16 (3) 24-12-26-18 (5) 22 (9-10-32 (45) 46) 35 (42-26) 23 (11-31) 44) 41-30 (37 (49) 50) 15-33 (47) 48) 36-34 (38 (51) 52) 19 (6) 27 (43-36) 14-29-21 (8-2) 17 (4) 25 (40-29) 13-28 (20) 39-24 / h7,12-14,18,22,30,39,43H, 1,8-11,15H2,2-6H3, (H , 41,44) (H, 45,46) (H, 47,48) (H, 49,50) (H, 51,52) / b24-12-, 25-13-, 26-12-, 27 -14-, 28-13-, 29-14-, 35-23-, 36-23- / t18-, 22-, 30- / m0 / s1 ; Kalit: VSEIDZLLWQQJGK-WSUYNKMOSA-N ;
	(bu nima?) (tasdiqlash)

Talaporfin

Talaporfin (KARVONSAROY, shuningdek, nomi bilan tanilgan aspartil xlor, mono-L-aspartil xlor e6, NPe6, yoki LS11) a xlor asoslangan fotosensitizator ichida ishlatilgan fotodinamik terapiya (TINCH OKEANI KUNDUZGI VAQTI).

Odatda bu to'lqin uzunligiga moslashtirilgan lazer bilan ta'minlangan 664-667 nm qizil nurni yutadi.^[1]

Uchun Yaponiyada (2004 yilda) tasdiqlangan Tinch okeani kunduzgi vaqti o'pka saratoni va Lazerfirin.^[2]

Adabiyotlar

^ Usuda J, Kato H, Okunaka T, Furukava K, Tsutsui H, Yamada K, Suga Y, Honda H, Nagatsuka Y, Ohira T, Tsuboi M, Xirano T (iyun 2006). "O'pka saratoniga qarshi fotodinamik terapiya (PDT)". Ko'krak qafasi onkologiyasi jurnali: O'pka saratonini o'rganish xalqaro assotsiatsiyasining rasmiy nashri. 1 (5): 489–93. doi:10.1016 / S1556-0864 (15) 31616-6. PMID 17409904.
^ Usuda J, Kato H, Okunaka T, Furukava K, Honda H, Suga Y, Xirata T, Ohira T, Tsuboi M, Xirano T (iyun 2006). "O'pka saratonining dastlabki bosqichida markazlashgan holda lazerfirin yordamida fotodinamik terapiya". Klinik onkologiya jurnali. 24 (18 ta ilova): 7229.

Ekstrakorporeal foto-immunoterapiya aylanma shish hujayralari uchun

[pmid17409904-1] Usuda J, Kato H, Okunaka T, Furukava K, Tsutsui H, Yamada K, Suga Y, Honda H, Nagatsuka Y, Ohira T, Tsuboi M, Xirano T (iyun 2006). "O'pka saratoniga qarshi fotodinamik terapiya (PDT)". Ko'krak qafasi onkologiyasi jurnali: O'pka saratonini o'rganish xalqaro assotsiatsiyasining rasmiy nashri. 1 (5): 489–93. doi:10.1016 / S1556-0864 (15) 31616-6. PMID 17409904.

[2] Usuda J, Kato H, Okunaka T, Furukava K, Honda H, Suga Y, Xirata T, Ohira T, Tsuboi M, Xirano T (iyun 2006). "O'pka saratonining dastlabki bosqichida markazlashgan holda lazerfirin yordamida fotodinamik terapiya". Klinik onkologiya jurnali. 24 (18 ta ilova): 7229.

[1]

[2]

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WikiDer > Talaporfin

Adabiyotlar

Klinik ma'lumotlar

AHFS/Drugs.com	Giyohvand moddalarning xalqaro nomlari
Marshrutlari ma'muriyat	IV
ATC kodi	yo'q
Huquqiy holat
Huquqiy holat	Umuman olganda: ℞ (faqat retsept bo'yicha)
Identifikatorlar
IUPAC nomi N-{[(2S,3S) -7-karboksi-3- (2-karboksietil) -12-etil-2,8,13,18-tetrametil-17-vinil-2,3-dihidroporfirin-5-il] atsetil} -L-aspartik kislota
CAS raqami	110230-98-3^Y 220201-34-3 (natriy tuzi)
PubChem CID	5486799
ChemSpider	16737134^N
UNII	P4ROX5ELT2
Kimyoviy va fizik ma'lumotlar
Formula	C₃₈H₄₁N₅O₉
Molyar massa	711.772 g · mol⁻¹
3D model (JSmol)	Interaktiv rasm
Jilmayganlar CCC1 = C2C = C3C (= C (C (= N3) C (= C4 [C @ H] ([C @@ H) (C (= N4) C = C5C (= C (C (= CC (= C1C) ) N2) N5) C = C) C) C) CCC (= O) O) CC (= O) N [C @@ H] (CC (= O) O) C (= O) O) C (=) O) O) C
InChI InChI = 1S / C38H41N5O9 / c1-7-20-16 (3) 24-12-26-18 (5) 22 (9-10-32 (45) 46) 35 (42-26) 23 (11-31) 44) 41-30 (37 (49) 50) 15-33 (47) 48) 36-34 (38 (51) 52) 19 (6) 27 (43-36) 14-29-21 (8-2) 17 (4) 25 (40-29) 13-28 (20) 39-24 / h7,12-14,18,22,30,39,43H, 1,8-11,15H2,2-6H3, (H , 41,44) (H, 45,46) (H, 47,48) (H, 49,50) (H, 51,52) / b24-12-, 25-13-, 26-12-, 27 -14-, 28-13-, 29-14-, 35-23-, 36-23- / t18-, 22-, 30- / m0 / s1^N Kalit: VSEIDZLLWQQJGK-WSUYNKMOSA-N^N
^NY (bu nima?) (tasdiqlash)