WikiDer > Tilmikosin

Tilmikosin
Ismlar
	IUPAC nomi [(2R,3R,4E,6E,9R,11R,12S,13S,14R) -12 - {[3,6-Dideoksi-3- (dimetilamino) -β-D.-glukopiranosil] oksi} -11- {2 - [(3R,5S) -3,5-dimetilpiperidin-1-il] etil} -2-etil-14-gidroksi-5,9,13-trimetil-8,16-dioksooksatsikloheksadeka-4,6-dien-3-yl] metil 6- deoksi-2,3-di-O-metil-β-D.-allopiranozid
	Boshqa ismlar Mikotil; 20-Deoksi-20- (3,5-dimetilpiperidin-1-il) -desmikozin
Identifikatorlar
CAS raqami	108050-54-0 ;
3D model (JSmol)	Interaktiv rasm;
ChEMBL	ChEMBL206342;
ChemSpider	4445656;
ECHA ma'lumot kartasi	100.167.324
PubChem CID	16667713;
UNII	XL4103X2E3;
CompTox boshqaruv paneli (EPA)	DTXSID5046011 ;
	InChI InChI = 1S / C46H80N2O13 / c1-13-36-33 (24-57-46-44 (56-12) 43 (55-11) 40 (53) 31 (8) 59-46) 19-25 (2)) 14-15-34 (49) 28 (5) 20-32 (16-17-48-22-26 (3) 18-27 (4) 23-48) 42 (29 (6) 35 (50) 21-) 37 (51) 60-36) 61-45-41 (54) 38 (47 (9) 10) 39 (52) 30 (7) 58-45 / h14-15,19,26-33,35-36, 38-46,50,52-54H, 13,16-18,20-24H2,1-12H3 / b15-14 +, 25-19 + / t26-, 27 +, 28-, 29 +, 30-, 31 -, 32 +, 33-, 35-, 36-, 38 +, 39-, 40-, 41-, 42-, 43-, 44-, 45 +, 46- / m1 / s1 Kalit: JTSDBFGMPLKDCD-XVFHVFLVSA-N; InChI = 1 / C46H80N2O13 / c1-13-36-33 (24-57-46-44 (56-12) 43 (55-11) 40 (53) 31 (8) 59-46) 19-25 (2)) 14-15-34 (49) 28 (5) 20-32 (16-17-48-22-26 (3) 18-27 (4) 23-48) 42 (29 (6) 35 (50) 21-) 37 (51) 60-36) 61-45-41 (54) 38 (47 (9) 10) 39 (52) 30 (7) 58-45 / h14-15,19,26-33,35-36, 38-46,50,52-54H, 13,16-18,20-24H2,1-12H3 / b15-14 +, 25-19 + / t26-, 27 +, 28-, 29 +, 30-, 31 -, 32 +, 33-, 35-, 36-, 38 +, 39-, 40-, 41-, 42-, 43-, 44-, 45 +, 46- / m1 / s1 Kalit: JTSDBFGMPLKDCD-XVFHVFLVBD;
	Jilmayganlar O = C4 C = C C (= C [C @ H] (CO [C @@ H] 1O [C @ H] (C) [C @@ H] (O) [C @@ H] (OC) [C @ H] 1OC) [C @ H] (OC (= O) C [C @@ H] (O) [C @@ H] ([C @@ H] (O [C @@) H] 2O [C @@ H] ([C @@ H] (O) [C @ H] (N (C) C) [C @ H] 2O) C) [C @@ H] (CCN3C [C @H] (C) C [C @ H] (C) C3) C [C @ H] 4C) C) CC) C;
Xususiyatlari
Kimyoviy formulalar	C46H80N2O13
Molyar massa	869.147 g · mol−1
Suvda eruvchanligi	566 mg / ml
Farmakologiya
ATCvet kodi	QJ01FA91 (JSSV)
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

Tilmicosin

Tilmikosin a makrolid antibiotik. Veterinariya tibbiyotida davolash uchun ishlatiladi sigirning nafas olish kasalligi va enzootik pnevmoniya sabab bo'lgan Mannheimiya (Pasteurella) gemolitikasi qo'ylarda.^[2] Odamlarda Tilmikosin AOK qilinganida 1 millilitrdan katta miqdorda o'limga olib keladigan kardiotoksik ta'sirga olib keladi, bu ko'pincha veterinariya xodimlari va fermerlarda kuzatiladi. ^[3]

Adabiyotlar

^ ^a ^b Tilmikosin, Birlashgan Millatlar Tashkilotining Oziq-ovqat va qishloq xo'jaligi tashkiloti
^ Micotil 300 yangi hayvonlarga dori vositasi, Amerika Qo'shma Shtatlari oziq-ovqat va farmatsevtika idorasi
^ Mikotil (tilmikosin) - Dori vositalarining salbiy reaktsiyalari - Veterinariya preparatlari, Veterinariya dori vositalari direksiyasi

[fao-1] Tilmikosin, Birlashgan Millatlar Tashkilotining Oziq-ovqat va qishloq xo'jaligi tashkiloti

[2] Micotil 300 yangi hayvonlarga dori vositasi, Amerika Qo'shma Shtatlari oziq-ovqat va farmatsevtika idorasi

[3] Mikotil (tilmikosin) - Dori vositalarining salbiy reaktsiyalari - Veterinariya preparatlari, Veterinariya dori vositalari direksiyasi

[1]

[2]

[3]

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WikiDer > Tilmikosin

Adabiyotlar

Ismlar

IUPAC nomi [(2R,3R,4E,6E,9R,11R,12S,13S,14R) -12 - {[3,6-Dideoksi-3- (dimetilamino) -β-D.-glukopiranosil] oksi} -11- {2 - [(3R,5S) -3,5-dimetilpiperidin-1-il] etil} -2-etil-14-gidroksi-5,9,13-trimetil-8,16-dioksooksatsikloheksadeka-4,6-dien-3-yl] metil 6- deoksi-2,3-di-O-metil-β-D.-allopiranozid
Boshqa ismlar Mikotil; 20-Deoksi-20- (3,5-dimetilpiperidin-1-il) -desmikozin^[1]
Identifikatorlar
CAS raqami	108050-54-0^Y
3D model (JSmol)	Interaktiv rasm
ChEMBL	ChEMBL206342
ChemSpider	4445656
ECHA ma'lumot kartasi	100.167.324
PubChem CID	16667713
UNII	XL4103X2E3
CompTox boshqaruv paneli (EPA)	DTXSID5046011
InChI InChI = 1S / C46H80N2O13 / c1-13-36-33 (24-57-46-44 (56-12) 43 (55-11) 40 (53) 31 (8) 59-46) 19-25 (2)) 14-15-34 (49) 28 (5) 20-32 (16-17-48-22-26 (3) 18-27 (4) 23-48) 42 (29 (6) 35 (50) 21-) 37 (51) 60-36) 61-45-41 (54) 38 (47 (9) 10) 39 (52) 30 (7) 58-45 / h14-15,19,26-33,35-36, 38-46,50,52-54H, 13,16-18,20-24H2,1-12H3 / b15-14 +, 25-19 + / t26-, 27 +, 28-, 29 +, 30-, 31 -, 32 +, 33-, 35-, 36-, 38 +, 39-, 40-, 41-, 42-, 43-, 44-, 45 +, 46- / m1 / s1 Kalit: JTSDBFGMPLKDCD-XVFHVFLVSA-N InChI = 1 / C46H80N2O13 / c1-13-36-33 (24-57-46-44 (56-12) 43 (55-11) 40 (53) 31 (8) 59-46) 19-25 (2)) 14-15-34 (49) 28 (5) 20-32 (16-17-48-22-26 (3) 18-27 (4) 23-48) 42 (29 (6) 35 (50) 21-) 37 (51) 60-36) 61-45-41 (54) 38 (47 (9) 10) 39 (52) 30 (7) 58-45 / h14-15,19,26-33,35-36, 38-46,50,52-54H, 13,16-18,20-24H2,1-12H3 / b15-14 +, 25-19 + / t26-, 27 +, 28-, 29 +, 30-, 31 -, 32 +, 33-, 35-, 36-, 38 +, 39-, 40-, 41-, 42-, 43-, 44-, 45 +, 46- / m1 / s1 Kalit: JTSDBFGMPLKDCD-XVFHVFLVBD
Jilmayganlar O = C4 C = C C (= C [C @ H] (CO [C @@ H] 1O [C @ H] (C) [C @@ H] (O) [C @@ H] (OC) [C @ H] 1OC) [C @ H] (OC (= O) C [C @@ H] (O) [C @@ H] ([C @@ H] (O [C @@) H] 2O [C @@ H] ([C @@ H] (O) [C @ H] (N (C) C) [C @ H] 2O) C) [C @@ H] (CCN3C [C @H] (C) C [C @ H] (C) C3) C [C @ H] 4C) C) CC) C
Xususiyatlari
Kimyoviy formulalar	C₄₆H₈₀N₂O₁₃
Molyar massa	869.147 g · mol⁻¹
Suvda eruvchanligi	566 mg / ml^[1]
Farmakologiya
ATCvet kodi	QJ01FA91 (JSSV)
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari