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Vapreotid
Klinik ma'lumotlar
Savdo nomlari	Sanvar
Boshqa ismlar	H-D-Phe-Cys (1) -Tyr-D-Trp-Lys-Val-Cys (1) -Trp-NH2; Oktastatin
ATC kodi	H01CB04 (JSSV) ;
Farmakokinetik ma'lumotlar
Yo'q qilish yarim hayot	30 daqiqa
Identifikatorlar
	IUPAC nomi D-fenilalanil-L-sisteinil-L-tirozil-D-triptofil-L-lizil-L-valil-L-sisteinil-L-triptofanamid (2-> 7) -disulfid;
CAS raqami	103222-11-3;
PubChem CID	23725064;
PubChem SID	46506923;
DrugBank	DB04894;
ChemSpider	64425;
UNII	2PK59M9GFF;
KEGG	D06281;
CompTox boshqaruv paneli (EPA)	DTXSID00883113 ;
Kimyoviy va fizik ma'lumotlar
Formula	C57H70N12O9S2
Molyar massa	1131.38 g · mol−1
3D model (JSmol)	Interaktiv rasm;
Zichlik	1,4 g / sm3
Qaynatish nuqtasi	1,540,9 ° S (2,805,6 ° F)
	Jilmayganlar CC (C) [C @ H] 1C (= O) N [C @@ H] (CSSC [C @@ H] (C (= O) N [C @ H] (C (= O) N [C) @@ H] (C (= O) N [C @ H] (C (= O) N1) CCCCN) Cc2c [nH] c3c2cccc3) Cc4ccc (cc4) O) NC (= O) [C @@ H] ( Cc5ccccc5) N) C (= O) N [C @@ H] (Cc6c [nH] c7c6cccc7) C (= O) N;
	InChI InChI = 1S / C57H70N12O9S2 / c1-32 (2) 49-57 (78) 68-48 (55 (76) 64-44 (50 (60) 71) 26-35-28-61-41-16-8- 6-14-38 (35) 41) 31-80-79-30-47 (67-51 (72) 40 (59) 24-33-12-4-3-5-13-33) 56 (77) 65-45 (25-34-19-21-37 (70) 22-20-34) 53 (74) 66-46 (27-36-29-62-42-17-9-7-15-39 ( 36) 42) 54 (75) 63-43 (52 (73) 69-49) 18-10-11-23-58 / h3-9,12-17,19-22,28-29,32,40, 43-49,61-62,70H, 10-11,18,23-27,30-31,58-59H2,1-2H3, (H2,60,71) (H, 63,75) (H, 64) , 76) (H, 65,77) (H, 66,74) (H, 67,72) (H, 68,78) (H, 69,73) / t40-, 43 +, 44 +, 45 + , 46-, 47 +, 48 +, 49 + / m1 / s1; Kalit: SWXOGPJRIDTIRL-DOUNNPEJSA-N;

Vapreotide

Vapreotid (Sanvar) sintetik hisoblanadi somatostatin analog. U davolashda ishlatiladi qizilo'ngachning varikulyar qonashlari sirotik bilan og'rigan bemorlarda jigar kasalligi va OITS-bog'liq diareya.^[1]

Bu H-D-Phe-Cys (1) -Tyr-D-Trp-Lys-Val-Cys (1) -Trp-NH2 ketma-ketligi bo'lgan 8 ta qoldiq peptid.

Adabiyotlar

^ DrugBank DB04894

Bu gormonal preparat maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[DrugBank-1] DrugBank DB04894

[1]

v t e GH/IGF-1 o'qi signal berish modulyatorlar
GH (somatotropin)	Agonistlar: Albusomatropin Sigir somatotropini Efpegsomatropin Eftansomatropin alfa O'sish gormoni Inson platsenta laktogeni Plasenta o'sish gormoni (o'sish gormoni varianti) Somagrebove Somapatsitan Somatosalm Somatotropin Somatropin pegol Somatrem Bir narsa Somatrogon (MOD-4023; hGH-CTP) Somavaratan Somavubove Somidobove Antagonistlar: G120K-hGH Pegvisomant Antisense oligonukleotidlari: Atesidorsen Majburiy oqsillar: GHBP
GHIH (somatostatin)	Agonistlar: BIM-23052 CH-275 Kortistatin-14 Depreotid Edotreotid Ilatreotid L-803,087 L-817,818 Lanreotid NNC 26-9100 Oktreotat Oktreotid Pasireotid Pentetreotid RC-160 Seglitid Somatostatin (GHIH) Somatostatin (1-28) SRIF-14 SRIF-28 TT-232 Vapreotid Veldoreotid Antagonistlar: BIM-23056 Siklosomatostatin CYN-154806 Satoreotid
GHRH (somatokrinin)	Agonistlar: Peptid: ALRN-5281 CJC-1295 Dumorelin GHRH O'zgartirilgan GRF (1-29) Rismorelin Sermorelin Somatorelin Tesamorelin Antagonistlar: MZ-5-156
GHS (grelin)	Agonistlar: Peptid: Aleksamorelin Kortistatin-14 EP-51216 Examorelin (hexarelin) Grelin GHRP-1 GHRP-3 GHRP-4 GHRP-5 GHRP-6 Ipamorelin Lenomorelin Livoletid LY-444711 Pralmorelin (GHRP-2) Relamorelin Tabimorelin Ulimorelin; Peptid bo'lmagan: Adenozin Anamorelin Kapromorelin CP-464709 Ibutamoren (MK-677) L-692,585 Macimorelin SM-130686; Saralanmagan: LY-426410 LY-444711 Antagonistlar: A-778193 Kortistatin-8 (D.-Lys³) -GHRP-6 JMV 2959 YIL-781
IGF-1 (somatomedin)	Qarang Bu yerga o'rniga.
Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari • Signal peptid / oqsil retseptorlari modulyatorlari

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