WikiDer > Evenamid

Evenamid
Klinik ma'lumotlar
Boshqa ismlar	NW-3509; NW-3509A
ATC kodi	Yo'q;
Identifikatorlar
	IUPAC nomi 2- [2- (3-butoksifenil) etilamino] -N,N-dimetilatsetamid;
CAS raqami	1092977-61-1 ;
PubChem CID	25105689;
ChemSpider	44208827;
UNII	ON5S6N53JS;
Kimyoviy va fizik ma'lumotlar
Formula	C16H26N2O2
Molyar massa	278.396 g · mol−1
3D model (JSmol)	Interaktiv rasm;
	Jilmayganlar CCCCOC1 = CC = CC (= C1) CCNCC (= O) N (C) C;
	InChI InChI = 1S / C16H26N2O2 / c1-4-5-11-20-15-8-6-7-14 (12-15) 9-10-17-13-16 (19) 18 (2) 3 / h6- 8,12,17H, 4-5,9-11,13H2,1-3H3; Kalit: GRHBODILPPXVKN-UHFFFAOYSA-N;

Evenamide

Evenamid (KARVONSAROY) (rivojlanish kodlari nomlari NW-3509, NW-3509A) a tanlangan kuchlanishli natriy kanali bloker, shu jumladan (va ular bilan cheklanmagan) kichik tiplar Na_v1.3, Na_v1.7va Na_v1.8deb tavsiflanadi antipsikotik va Newron Pharmaceuticals tomonidan ishlab chiqilgan qo'shimcha terapiya davolash uchun shizofreniya.^[1]^[2]^[3]^[4] Preparat samaradorligini ko'rsatdi hayvon modellari ning psixoz, mani, depressiyava tajovuz.^[3] Tugadi I bosqich klinik sinovlarva II bosqich klinik sinovlar 2015 yilning uchinchi choragida boshlanadi.^[5]

Shuningdek qarang

Tergov qilinadigan antipsikotiklar ro'yxati

Adabiyotlar

^ "Shizofreniyada giyohvand moddalarni rivojlantirish: xulosa va jadval". Farmatsevtika tibbiyoti. 28 (5): 265–271. 2014. doi:10.1007 / s40290-014-0070-6. ISSN 1178-2595. S2CID 8513976.
^ Tibbiy kimyo taraqqiyoti. Elsevier. 6 oktyabr 2010. 81- bet. ISBN 978-0-12-381293-3.
^ ^a ^b Gupta SP (2011 yil 21-iyun). Ion kanallari va ularning inhibitorlari. Springer Science & Business Media. 102– betlar. ISBN 978-3-642-19922-6.
^ Zuliani V, Amori L, Rivara M (2011). "Natriy kanal blokerlarini loyihalash va ishlab chiqishdagi yutuqlar". Ion kanallari va ularning inhibitorlari. 79–115-betlar. doi:10.1007/978-3-642-19922-6_4. ISBN 978-3-642-19921-9.
^ "Nevron nevrologik terapiyani rivojlantirishni davom ettirish uchun yangi mablag 'yig'di". Labiotech. 5 Fevral 2015. Arxivlangan asl nusxasi 2016 yil 4 martda.

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[1] "Shizofreniyada giyohvand moddalarni rivojlantirish: xulosa va jadval". Farmatsevtika tibbiyoti. 28 (5): 265–271. 2014. doi:10.1007 / s40290-014-0070-6. ISSN 1178-2595. S2CID 8513976.

[2] Tibbiy kimyo taraqqiyoti. Elsevier. 6 oktyabr 2010. 81- bet. ISBN 978-0-12-381293-3.

[Gupta2011-3] Gupta SP (2011 yil 21-iyun). Ion kanallari va ularning inhibitorlari. Springer Science & Business Media. 102– betlar. ISBN 978-3-642-19922-6.

[ZulianiAmori2011-4] Zuliani V, Amori L, Rivara M (2011). "Natriy kanal blokerlarini loyihalash va ishlab chiqishdagi yutuqlar". Ion kanallari va ularning inhibitorlari. 79–115-betlar. doi:10.1007/978-3-642-19922-6_4. ISBN 978-3-642-19921-9.

[Labiotech-5] "Nevron nevrologik terapiyani rivojlantirishni davom ettirish uchun yangi mablag 'yig'di". Labiotech. 5 Fevral 2015. Arxivlangan asl nusxasi 2016 yil 4 martda.

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v t e Antipsikotiklar (N05A)
Odatda	Butirofenonlar: Benperidol Bromperidol Droperidol Haloperidol^# Moperon Pipamperon Spiperon Timiperone Trifluperidol Difenilbutilpiperidinlar: Fluspirilen Penfluridol Pimozid Fenotiyazinlar: Asetofenazin Butaperazin Karfenazin (karfenazin)^‡ Xlorpromazin Cyamemazine Diksirazin Flüfenazin Levomepromazin (metotrimeprazin) Mesoridazin Perazin Periciazin Perfenazin Piperatsetazin Pipotiazin Proxlorperazin Promazin Sulforidazin Tiyopropazat Tioproperazin Tioridazin Trifluoperazin Triflupromazin Tioksantenlar: Xlorprotixen Klopentiksol Flupentiksol Tiotiksen (tiyotiksen) Zuklopentiksol
Bahsli	Benzamidlar: Amisulprid Levosulpirid Nemonaprid Remoksiprid^‡ Sulpirid Sultoprid Tiaprid Veraliprid^‡ Butirofenonlar: Melperone Trisikliklar: Karpipramin Klokapramin Klorotepin Clotiapine Loksapin Mosapramin Boshqalar: Molindone
Atipik	Benzisoksazol/benzizotiyazollar: Iloperidon Lurasidon Paliperidon Paliperidon palmitati Perospiron Risperidon^# Ziprasidon Butirofenonlar: Lumateperon Fenilpiperazinlar/kinolinonlar: Aripiprazol Aripiprazol lauroksil Brilaroksazin^† Brexpiprazol Kariprazin Trisikliklar: Asenapin Klozapin^# Olanzapin Ketiapin Zotepin Boshqalar: Blonanserin Pimavanserin Sertindol
Boshqalar	Azatsiklonol Kannabidiol Oksipertin Reserpine Tetrabenazin
^#JSST-EM ^‡Olingan bozordan Klinik sinovlar: ^†III bosqich ^§Hech qachon III bosqichga

v t e Fenetilaminlar
Fenetilaminlar	Psixelika: 25B-NBOMe 25C-NBOMe 25D-NBOMe 25I-NBOMe 25N-NBOMe 2C-B 2C-B-AN 2C-Bn 2C-Bu 2C-C 2C-CN 2C-CP 2C-D 2C-E 2C-EF 2C-F 2C-G 2C-G-1 2C-G-2 2C-G-3 2C-G-4 2C-G-5 2C-G-6 2C-G-N 2C-H 2C-I 2C-iP 2C-N 2C-NH2 2C-O 2C-O-4 2C-P 2C-Ph 2C-SE 2C-T 2C-T-2 2C-T-3 2C-T-4 2C-T-5 2C-T-6 2C-T-7 2C-T-8 2C-T-9 2C-T-10 2C-T-11 2C-T-12 2C-T-13 2C-T-14 2C-T-15 2C-T-16 2C-T-17 2C-T-18 2C-T-19 2C-T-20 2C-T-21 2C-T-22 2C-T-22.5 2C-T-23 2C-T-24 2C-T-25 2C-T-27 2C-T-28 2C-T-30 2C-T-31 2C-T-32 2C-T-33 2C-TFE 2C-TFM 2C-YN 2C-V Allyselkalin DESOKSI Eskalin Izoproskalin Jimkalin Makromerin MEPEA Meskalin Meteskalin Metalleskalin Proskalin Psi-2C-T-4 TCB-2 Venlafaksin Stimulyatorlar: Feniletanolamin Hordenine Fenetilamin a-metilfenetilamin (amfetamin) b-metilfenetilamin m-Metilfenetilamin N-Metilfenetilamin o-Metilfenetilamin p-Metilfenetilamin Metilfenidat Entaktogenlar: Lopofin MDPEA MDMPEA Boshqalar: BOH DMPEA
Amfetaminlar	Psixelika: 3C-BZ 3C-E 3C-P Alef Beatris Bromo-DragonFLY D-Deprenil DMA DMCPA DMMDA DOB DOC DOEF DOET DOI DOM DON DOPR DOTFM Ganesha MMDA MMDA-2 Psi-DOM TMA TeMA Stimulyatorlar: 2-FA 2-FMA 3-FA 3-FMA Acridorex Alfetamin Amfekloral Amfepentorex Amfetamin (Dekstroamfetamin, Levoamfetamin) Amfetaminil Benfloreks Benzfetamin Ketin Klobenzoreks Dimetilamfetamin Efedrin Etilamfetamin Fencamfamin Fenkamin Fenetillin Fenfluramin (Dexfenfluramin, Levofenfluramin) Fenproporeks Flucetorex Fludoreks Formetorex Furfenoreks Gefefrin 4-gidroksiamfetamin Iofetamin Izopropilamfetamin Lefetamin Lisdexamfetamin Mefenorex Metaraminol Metamfetamin (Dekstrometamfetamin, Levometamfetamin) Metoksifenamin MMA Morforex Norfenfluramin L -Norsevdoefedrin N, alfa-dietilfeniletilamin Oxifentorex Oksilofrin Ortetamin PBA PCA Fenprometamin PFA PFMA PIA PMA PMEA PMMA Fenilpropanolamin Fledrin Prenilamin Propilamfetamin Psödoefedrin Sibutramin Tifloreks Tranilsipromin Ksilopropamin Zilofuramin Entaktogenlar: 4-FA 4-FMA 4-MA 4-MMA 4-MTA 5-APB 5-APDB 5-EAPB 5-IT 5-MAPB 5-MAPDB 6-APB 6-APDB 6-Xloro-MDMA 6-EAPB 6-IT 6-MAPB 6-MAPDB EDA IAP 2,3-MDA 3,4-MDA (tenamfetamin) MDEA MDHMA MDMA (midomafetamin) MDOH Metamnetamin MMDMA Naftilaminopropan TAP Boshqalar: 3,4-DCA Amiflamin DiFMDA Selegilin (shuningdek D. -Deprenil)
Fenterminalar	Stimulyatorlar: Xlorfentermin Cloforex Klortermin Etolorex Mefentermin Pentorex Phentermine Entaktogenlar: MDPH MDMPH Boshqalar: Seriklamin
Katinonlar	Stimulyatorlar: 3-FMC 4-MC 4-BMC 4-CMC 4-EMC 4-FMC 4-MEC 4-MeMABP 4-MPD Amfepramon Benzedron Brephedron Bufedron Bupropion Katinon Dimetilkatinon Etkatinon Evtilon Gidroksibupropion Metkatinon Methedron NEB N-etilheksedron N-etilpentrone Pentrone Pentilon Radafaksin Entaktogenlar: 3,4-DMMC 3-MMC Butilon Etilon Metilon Metilenedioksikatinon Mefedron
Fenilizobutilaminlar	Entaktogenlar: 4-CAB 4-MAB Ariadne BDB Butilon EBDB Evtilon MBDB Stimulyatorlar: Fenilizobutilamin
Fenilalkilpirrolidinlar	Stimulyatorlar: a-PBP a-PHP a-PPP a-PVP MDPBP MDPPP MDPV 4-MePBP 4-MePHP 4-MePPP MOPPP MOPVP MPBP MPHP MPPP Nafiron PEP Prolintan Pirovaleron
Katekolaminlar (va yaqin qarindoshlari)	6-FNE 6-OHDA a-Me-DA a-Me-TRA Adrenoxrom Siladopa D. -DOPA (Dekstrodopa) Dimetofrin Dopamin Epinefrin Epinin Etilefrin Etilnorepinefrin Fenklonin Ibopamin Izoprenalin Isoetarin L -DOPA (Levodopa) L -DOPS (Droksidopa) L -Fenilalanin L -Tirozin m-Tiramin Metanefrin Metaraminol Metaterol Metirozin Metildopa N, N-dimetildopamin Nordefrin (Levonordefrin) Norepinefrin Norfenefrin (m-Oktopamin) Normetanephrine Orsiprenalin p-Oktopamin p-Tiramin Fenilefrin Sinefrin
Turli xil	AL-LAD Amidefrin Arbutamin Kafedrin Denopamin Desvenlafaksin Difenidin Dizosilpin Dobutamin Dopeksamin Efenidin Etafedrin ETH-LAD Famprofazon Ftorolintan Geksapradol IP-LAD Lizerjik kislota amidi Liserjik kislota 2-butil amid Lizerjik kislota 2,4-dimetilazetidid Lizerjik kislota dietilamid Metoksamin Metoksfenidin MT-45 PARGY-LAD Phenibut PRO-LAD Pronetalol Salbutamol (Levosalbutamol) Solriamfetol Teodrenalin Tiamfenikol UWA-101

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