WikiDer > Norfenfluramin - Vikipediya

Norfenfluramin
Ismlar
	IUPAC nomi 1- [3- (Trifluorometil) fenil] propan-2-amin
	Boshqa ismlar 3-Trifluorometilamfetamin
Identifikatorlar
CAS raqami	19036-73-8 ;
3D model (JSmol)	Interaktiv rasm;
ChemSpider	15108 ;
IUPHAR / BPS	215;
PubChem CID	15897;
UNII	CLX07A6ZIY ;
CompTox boshqaruv paneli (EPA)	DTXSID60904717 ;
	InChI InChI = 1S / C10H12F3N / c1-7 (14) 5-8-3-2-4-9 (6-8) 10 (11,12) 13 / h2-4,6-7H, 5,14H2,1H3 Kalit: MLBHFBKZUPLWBD-UHFFFAOYSA-N ; InChI = 1 / C10H12F3N / c1-7 (14) 5-8-3-2-4-9 (6-8) 10 (11,12) 13 / h2-4,6-7H, 5,14H2,1H3 Kalit: MLBHFBKZUPLWBD-UHFFFAOYAR;
	Jilmayganlar FC (F) (F) c1cccc (c1) CC (N) C;
Xususiyatlari
Kimyoviy formulalar	C10H12F3N
Molyar massa	203.208 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	tasdiqlang (nima bu ?)
	Infobox ma'lumotnomalari

Norfenfluramine - Wikipedia

Norfenfluramin, yoki 3-trifluorometilamfetamin, hech qachon sotilmaydi dori ning amfetamin o'zini tutadigan oila serotonin va noradrenalin ozod qiluvchi agent va kuchli 5-HT_2A, 5-HT_2Bva 5-HT_2C agonist. Norfenfluraminning 5-HTga ta'siri_2B retseptorlari yoqilgan yurak klapanlari ko'payishidan keyin yurak etishmovchiligining o'ziga xos namunasiga olib keladi yurak fibroblastlar ustida triküspid qopqoqsifatida tanilgan yurak fibrozisi.^[1] Bu yon ta'sir ning olib chiqilishiga olib keldi fenfluramin sifatida anorektik agenti butun dunyo bo'ylab va uni olib qo'yishga benfloreks Evropada,^[2] chunki ikkala fenfluramin va benfluoreks norfenfluraminni an faol metabolit. Bu inson TAAR1 agonist.^[3]

Shuningdek qarang

Fenfluramin
Benfloreks
Norfenfluramin - bu kashfiyotchi fluketorex

Adabiyotlar

^ Setola, V .; Dukat, M.; Glennon, R. A .; Roth, B. L. (2005). "Valvulopatik anoreksigen Norfenfluraminning 5-HT bilan o'zaro ta'sirini molekulali aniqlagichlar_2B Retseptor " (PDF). Molekulyar farmakologiya. 68 (1): 20–33. doi:10.1124 / mol.104.009266. PMID 15831837. S2CID 30906680.
^ "Evropa dori agentligi benfloreksni Evropa Ittifoqi bozoridan chiqarishni tavsiya qiladi" (PDF). Evropa dorilar agentligi. 2009-12-18. Arxivlandi asl nusxasi (PDF) 2009-12-22 kunlari.
^ Lewin AH, Miller GM, Gilmour B (dekabr 2011). "Amin bilan bog'liq bo'lgan retseptorlari 1 amfetamin sinfidagi birikmalar uchun stereoelektiv bog'lanish joyidir". Bioorg. Med. Kimyoviy. 19 (23): 7044–8. doi:10.1016 / j.bmc.2011.10.007. PMC 3236098. PMID 22037049.

Bu dori ga tegishli maqola asab tizimi a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[1] Setola, V .; Dukat, M.; Glennon, R. A .; Roth, B. L. (2005). "Valvulopatik anoreksigen Norfenfluraminning 5-HT bilan o'zaro ta'sirini molekulali aniqlagichlar_2B Retseptor " (PDF). Molekulyar farmakologiya. 68 (1): 20–33. doi:10.1124 / mol.104.009266. PMID 15831837. S2CID 30906680.

[2] "Evropa dori agentligi benfloreksni Evropa Ittifoqi bozoridan chiqarishni tavsiya qiladi" (PDF). Evropa dorilar agentligi. 2009-12-18. Arxivlandi asl nusxasi (PDF) 2009-12-22 kunlari.

[pmid22037049-3] Lewin AH, Miller GM, Gilmour B (dekabr 2011). "Amin bilan bog'liq bo'lgan retseptorlari 1 amfetamin sinfidagi birikmalar uchun stereoelektiv bog'lanish joyidir". Bioorg. Med. Kimyoviy. 19 (23): 7044–8. doi:10.1016 / j.bmc.2011.10.007. PMC 3236098. PMID 22037049.

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v t e Fenetilaminlar
Fenetilaminlar	Psixelika: 25B-NBOMe 25C-NBOMe 25D-NBOMe 25I-NBOMe 25N-NBOMe 2C-B 2C-B-AN 2C-Bn 2C-Bu 2C-C 2C-CN 2C-CP 2C-D 2C-E 2C-EF 2C-F 2C-G 2C-G-1 2C-G-2 2C-G-3 2C-G-4 2C-G-5 2C-G-6 2C-G-N 2C-H 2C-I 2C-iP 2C-N 2C-NH2 2C-O 2C-O-4 2C-P 2C-Ph 2C-SE 2C-T 2C-T-2 2C-T-3 2C-T-4 2C-T-5 2C-T-6 2C-T-7 2C-T-8 2C-T-9 2C-T-10 2C-T-11 2C-T-12 2C-T-13 2C-T-14 2C-T-15 2C-T-16 2C-T-17 2C-T-18 2C-T-19 2C-T-20 2C-T-21 2C-T-22 2C-T-22.5 2C-T-23 2C-T-24 2C-T-25 2C-T-27 2C-T-28 2C-T-30 2C-T-31 2C-T-32 2C-T-33 2C-TFE 2C-TFM 2C-YN 2C-V Allyselkalin DESOKSI Eskalin Izoproskalin Jimkalin Makromerin MEPEA Meskalin Meteskalin Metalleskalin Proskalin Psi-2C-T-4 TCB-2 Venlafaksin Stimulyatorlar: Feniletanolamin Hordenine Fenetilamin a-metilfenetilamin (amfetamin) b-metilfenetilamin m-Metilfenetilamin N-Metilfenetilamin o-Metilfenetilamin p-Metilfenetilamin Metilfenidat Entaktogenlar: Lopofin MDPEA MDMPEA Boshqalar: BOH DMPEA
Amfetaminlar	Psixelika: 3C-BZ 3C-E 3C-P Alef Beatris Bromo-DragonFLY D-Deprenil DMA DMCPA DMMDA DOB DOC DOEF DOET DOI DOM DON DOPR DOTFM Ganesha MMDA MMDA-2 Psi-DOM TMA TeMA Stimulyatorlar: 2-FA 2-FMA 3-FA 3-FMA Acridorex Alfetamin Amfekloral Amfepentorex Amfetamin (Dekstroamfetamin, Levoamfetamin) Amfetaminil Benfloreks Benzfetamin Ketin Klobenzoreks Dimetilamfetamin Efedrin Etilamfetamin Fencamfamin Fenkamin Fenetillin Fenfluramin (Dexfenfluramin, Levofenfluramin) Fenproporeks Flucetorex Fludoreks Formetorex Furfenoreks Gefefrin 4-gidroksiamfetamin Iofetamin Izopropilamfetamin Lefetamin Lisdexamfetamin Mefenorex Metaraminol Metamfetamin (Dekstrometamfetamin, Levometamfetamin) Metoksifenamin MMA Morforex Norfenfluramin L -Norsevdoefedrin N, alfa-dietilfeniletilamin Oxifentorex Oksilofrin Ortetamin PBA PCA Fenprometamin PFA PFMA PIA PMA PMEA PMMA Fenilpropanolamin Fledrin Prenilamin Propilamfetamin Psödoefedrin Sibutramin Tifloreks Tranilsipromin Ksilopropamin Zilofuramin Entaktogenlar: 4-FA 4-FMA 4-MA 4-MMA 4-MTA 5-APB 5-APDB 5-EAPB 5-IT 5-MAPB 5-MAPDB 6-APB 6-APDB 6-Xloro-MDMA 6-EAPB 6-IT 6-MAPB 6-MAPDB EDA IAP 2,3-MDA 3,4-MDA (tenamfetamin) MDEA MDHMA MDMA (midomafetamin) MDOH Metamnetamin MMDMA Naftilaminopropan TAP Boshqalar: 3,4-DCA Amiflamin DiFMDA Selegilin (shuningdek D. -Deprenil)
Fenterminalar	Stimulyatorlar: Xlorfentermin Cloforex Klortermin Etolorex Mefentermin Pentorex Phentermine Entaktogenlar: MDPH MDMPH Boshqalar: Seriklamin
Katinonlar	Stimulyatorlar: 3-FMC 4-MC 4-BMC 4-CMC 4-EMC 4-FMC 4-MEC 4-MeMABP 4-MPD Amfepramon Benzedron Brephedron Bufedron Bupropion Katinon Dimetilkatinon Etkatinon Evtilon Gidroksibupropion Metkatinon Methedron NEB N-etilheksedron N-etilpentrone Pentrone Pentilon Radafaksin Entaktogenlar: 3,4-DMMC 3-MMC Butilon Etilon Metilon Metilenedioksikatinon Mefedron
Fenilizobutilaminlar	Entaktogenlar: 4-CAB 4-MAB Ariadne BDB Butilon EBDB Evtilon MBDB Stimulyatorlar: Fenilizobutilamin
Fenilalkilpirrolidinlar	Stimulyatorlar: a-PBP a-PHP a-PPP a-PVP MDPBP MDPPP MDPV 4-MePBP 4-MePHP 4-MePPP MOPPP MOPVP MPBP MPHP MPPP Nafiron PEP Prolintan Pirovaleron
Katekolaminlar (va yaqin qarindoshlari)	6-FNE 6-OHDA a-Me-DA a-Me-TRA Adrenoxrom Siladopa D. -DOPA (Dekstrodopa) Dimetofrin Dopamin Epinefrin Epinin Etilefrin Etilnorepinefrin Fenklonin Ibopamin Izoprenalin Isoetarin L -DOPA (Levodopa) L -DOPS (Droksidopa) L -Fenilalanin L -Tirozin m-Tiramin Metanefrin Metaraminol Metaterol Metirozin Metildopa N, N-dimetildopamin Nordefrin (Levonordefrin) Norepinefrin Norfenefrin (m-Oktopamin) Normetanephrine Orsiprenalin p-Oktopamin p-Tiramin Fenilefrin Sinefrin
Turli xil	AL-LAD Amidefrin Arbutamin Kafedrin Denopamin Desvenlafaksin Difenidin Dizosilpin Dobutamin Dopeksamin Efenidin Etafedrin ETH-LAD Famprofazon Ftorolintan Geksapradol IP-LAD Lizerjik kislota amidi Lizerjik kislota 2-butil amid Lizerjik kislota 2,4-dimetilazetidid Lizerjik kislota dietilamid Metoksamin Metoksfenidin MT-45 PARGY-LAD Phenibut PRO-LAD Pronetalol Salbutamol (Levosalbutamol) Solriamfetol Teodrenalin Tiamfenikol UWA-101

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WikiDer > Norfenfluramin - Vikipediya

Shuningdek qarang

Adabiyotlar

Ismlar


IUPAC nomi 1- [3- (Trifluorometil) fenil] propan-2-amin
Boshqa ismlar 3-Trifluorometilamfetamin
Identifikatorlar
CAS raqami	19036-73-8^Y
3D model (JSmol)	Interaktiv rasm
ChemSpider	15108^Y
IUPHAR / BPS	215
PubChem CID	15897
UNII	CLX07A6ZIY^Y
CompTox boshqaruv paneli (EPA)	DTXSID60904717
InChI InChI = 1S / C10H12F3N / c1-7 (14) 5-8-3-2-4-9 (6-8) 10 (11,12) 13 / h2-4,6-7H, 5,14H2,1H3^Y Kalit: MLBHFBKZUPLWBD-UHFFFAOYSA-N^Y InChI = 1 / C10H12F3N / c1-7 (14) 5-8-3-2-4-9 (6-8) 10 (11,12) 13 / h2-4,6-7H, 5,14H2,1H3 Kalit: MLBHFBKZUPLWBD-UHFFFAOYAR
Jilmayganlar FC (F) (F) c1cccc (c1) CC (N) C
Xususiyatlari
Kimyoviy formulalar	C₁₀H₁₂F₃N
Molyar massa	203.208 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Y tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari