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Enavatuzumab

Enavatuzumab
Monoklonal antikor
Turi	Butun antikor
Manba	Insoniylashtirilgan (dan.) sichqoncha)
Maqsad	TWEAK retseptorlari
Klinik ma'lumotlar
ATC kodi	yo'q
Identifikatorlar
CAS raqami	1062149-33-0^N
ChemSpider	yo'q
UNII	914910XFBB
KEGG	D09896
Kimyoviy va fizik ma'lumotlar
Formula	C₆₃₃₄H₉₇₉₂N₁₇₀₀O₂₀₀₀S₄₂
Molyar massa	143104.43 g · mol⁻¹
^NY (bu nima?) (tasdiqlash)

Enavatuzumab bu qattiq o'smalarni davolashda ishlatiladigan insonparvarlashtirilgan monoklonal antikor.

Enavatuzumab Facet Biotech Corp tomonidan ishlab chiqilgan.^[1]

Adabiyotlar

^ "USAN Kengashi tomonidan qabul qilingan nomuvofiq nom to'g'risidagi bayonot: Enavatuzumab" (PDF). Amerika tibbiyot assotsiatsiyasi.

Monoklonal antikorlar o'smalar uchun

Inson	Adekatumumab^§ Ascrinvacumab^§ Atezolizumab Cixutumumab^§ Konatumumab^§ Daratumumab Drozitumab^§ Duligotumab^§ Dusigitumab^§ Enfortumab vedotin Enoticumab^§ Figitumumab^§ Ganitumab^† Glembatumumab vedotin^† Intetumumab^§ Ipilimumab Iratumumab^§ Istiratumab Ikrucumab^§ Lexatumumab^§ Lucatumumab^§ Mapatumumab^§ Narnatumab^§ Necitumumab Nesvakumab^§ Nivolumab^# Ofatumumab Olaratumab^† Panitumumab Patritumab^§ Pembrolizumab^# Pritumumab^§ Radretumab^§ Ramucirumab Rilotumumab^† Robatumumab^§ Seribantumab^§ Tarextumab^§ Teprotumumab^† Tovetumab^§ Vantiktumab^§ Votumumab^§ Zalutumumab^† "-melu-" (melanoma) Flanvotumab^§
Sichqoncha	Altumomab pentetat Anatumomab mafenatoks Arcitumomab Bektumomab Blinatumomab Detumomab Ibritumomab tiuxetan Lilotomab Minretumomab Mitumomab Moxetumomab pasudotoks Naptumomab estafenatoks Nofetumomab merpentan Pemtumomab^† Pintumomab Racotumomab Satumomab pendetid Solitomab Taplitumomab paptoxi Tenatumomab Tositumomab 3F8 "-govo-" (tuxumdon o'smasi) Abagovomab Igovomab Oregovomab "-pro-" (prostata bezining shishi) Kapromab pendetid "-colo-" (yo'g'on ichak shishi) Edrecolomab Nacolomab tafenatoks
Ximerik	Amatuximab^§ Bavituximab^§ Brentuximab vedotin Karotuximab^† Cetuximab Derlotuximab biotin^§ Dinutuximab Ensituximab^§ Futuximab^§ Girentuximab^† Indatuximab ravtansine^§ Isatuximab Loncastuximab tesirine Margetuximab^† Rituximab^# Siltuximab Ublituximab^† IMAB362 "-mexi-" (melanoma): Ekromeximab^§
Insoniylashtirilgan	Abituzumab^§ Alemtuzumab Belantamab mafodotin Bevatsizumab Bivatuzumab mertansin^§ Brontictuzumab^§ Kantuzumab mertansin^§ Kantuzumab ravtansin^§ Cirmtuzumab Citatuzumab bogatoks^§ Clivatuzumab tetraxetan Cofetuzumab pelidotin Dacetuzumab^§ Demcizumab^§ Dalotuzumab^§ Denintuzumab mafodotin^§ Elotuzumab Emaktuzumab^§ Emibetuzumab^§ Enoblituzumab^§ Etaracizumab^§ Farletuzumab^§ Fiklatuzumab^§ Flotetuzumab^§ Gemtuzumab ozogamitsin Imgatuzumab^§ Inotuzumab ozogamitsin Labetuzumab^§ Lifastuzumab vedotin^§ Lintuzumab^§ Lorvotuzumab mertansin^§ Lumretuzumab^§ Matuzumab^§ Milatuzumab^§ Naxitamab Nimotuzumab^† Obinutuzumab Ocaratuzumab^§ Otlertuzumab^§ Onartuzumab^§ Oportuzumab monatoks^† Parsatuzumab^§ Pertuzumab Pinatuzumab vedotin^§ Polatuzumab vedotin Rosmantuzumab Rovalpituzumab tesirine^† Sacituzumab govitecan Sibrotuzumab^§ Simtuzumab^§ Tacatuzumab tetraxetan^§ Tigatuzumab^§ Trastuzumab^# Tucotuzumab celmoleukin^§ Vandortuzumab vedotin^§ Vanucizumab^§ Veltuzumab^§ Vorsetuzumab mafodotin^§ CBR96-doksorubitsin immunokonjugati PankoMab "-gozu-" (tuxumdon o'smasi) Sofituzumab vedotin^§
Sichqoncha / sichqoncha gibrid	Katumaxomab Ertumaxomab^§
Ximerik + insonparvarlashtirilgan	Depatuxizumab mafodotin^† Duvortuxizumab Ontuxizumab^§

^#JSST-EM
^‡Olingan bozordan
Klinik sinovlar:
- ^†III bosqich
- ^§Hech qachon III bosqichga

Sitokin retseptorlari modulyatorlar

Qarang Bu yerga o'rniga.

Eritropoetin	Agonistlar: ARA-290 Asialo eritropoetin Karbamillangan eritropoetin CNTO-530 Darbepoetin alfa Epoetin alfa Epoetin beta-versiyasi Epoetin deltasi Epoetin epsilon Epoetin gamma Epoetin kappa Epoetin omega Epoetin teta Epoetin zeta Eritropoetin (EPO) Eritropoetin-Fc Metoksi polietilen glikol-epoetin beta (CERA / Mircera) Peginesatide Pegol siematid (EPO-018B)
G-CSF (CSF3)	Agonistlar: Filgrastim Granulotsitlar koloniyasini stimulyatsiya qiluvchi omil Lenograstim Leridistim Lipegfilgrastim Nartograstim Pegfilgrastim Pegnartograstim
GM-CSF (CSF2)	Agonistlar: Ekogramostim Granulotsitlar makrofag koloniyasini stimulyatsiya qiluvchi omil Milodistim Molgramostim Regramostim Sargramostim Antikorlar: Mavrilimumab Namilumab Otilimab
M-CSF (CSF1)	Agonistlar: Cilmostim Interleykin-34 Lanimostim Makrofag koloniyasini stimulyatsiya qiluvchi omil Mirimostim Kinaz inhibitörleri: Agerafenib
SCF (c-to'plam)	Qarang Bu yerga o'rniga.
Trombopoetin	Agonistlar: Eltrombopag Pegakaristim Promegapoetin Romiplostim Trombopoetin (THPO, MGDF)

IFNAR (a / b, I)	Agonistlar: Albinterferon Interferon alfa (interferon alfa, IFN-a) Interferon alfa (IFNA1, IFNA2, IFNA4, IFNA5, IFNA6, IFNA7, IFNA8, IFNA10, IFNA13, IFNA14, IFNA16, IFNA17, IFNA21) Interferon alfa 2a Interferon alfa 2b Interferon alfa n1 Interferon alfakon-1 Interferon alfa-n3 Interferon beta-versiyasi (IFN-β) (IFNB1, IFNB3) Interferon beta 1a Interferon beta-1b Interferon kappa (IFN-ε / κ / τ / ζ, IFNK) Interferon omega (IFN-b, IFNW1) Peginterferon alfa-2a Peginterferon alfa-2b Antikorlar: Anifrolumab Faralimomab MEDI-545 Rontalizumab Sifalimumab Aldangan retseptorlari: Bifarsept
IFNGR (γ, II)	Agonistlar: Interferon gamma (IFN-γ) Interferon gamma 1b Antikorlar: Emapalumab Fontolizumab
IFNLR (λ, III)	IL-28R (IFNLR) ga qarang Bu yerga o'rniga.

Qarang Bu yerga o'rniga.

Qarang Bu yerga o'rniga.

Qarang Bu yerga o'rniga.

Boshqalar

JAK
(inhibitörler)

JAK1	Baritsitinib Filgotinib Momelotinib Oklacitinib Ruxolitinib Tofatsitinib (tasositinib, CP-690550) Upadatsitinib
JAK2	AG-490 Atiprimod AZD-1480 Baritsitinib CHZ868 Kukurbitatsin I (elateritsin B, JSI-124) CYT387 Lestaurtinib NSC-7908 NSC-33994 Pakritinib Ruxolitinib SD-1008 Tofatsitinib (tasositinib, CP-690550)
JAK3	AG-490 Serkosporamid Decernotinib (VX-509) TCS-21311 Tofatsitinib (tasositinib, CP-690550) WHI-P 154 ZM-39923 ZM-449829

Boshqalar

Qo'shimcha sitokinlar: Kardiotrofin 1 (CT-1)
FMSga o'xshash tirozin kinaz 3 ligand (FLT3L)
Leykemiya / leykotsitlar inhibitori omili (LIF)
Onkostatin M (OSM)
Timik stromal limfopoietin (TSLP)

Qo'shimcha sitokin retseptorlari modulyatorlari: Emfilermin
Lestaurtinib
Midostaurin
Quizartinib
Sorafenib
Sunitinib

Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari; Signal peptid / oqsil retseptorlari modulyatorlari; O'sish omili retseptorlari modulyatorlari

Bu monoklonal antikor- tegishli maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

Bu antineoplastik yoki immunomodulyatsion dori maqola a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.