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Imetit

Imetit
Ismlar

IUPAC nomi 2-(1H-imidazol-5-il) etil karbamimidotioat
Identifikatorlar
CAS raqami	102203-18-9^Y
3D model (JSmol)	Interaktiv rasm Interaktiv rasm
ChEMBL	ChEMBL19439^N
ChemSpider	3564^N
IUPHAR / BPS	1250
PubChem CID	3692
UNII	677MJ4VPZC^N
CompTox boshqaruv paneli (EPA)	DTXSID8043737
InChI InChI = 1S / C6H10N4S / c7-6 (8) 11-2-1-5-3-9-4-10-5 / h3-4H, 1-2H2, (H3,7,8) (H, 9, 10)^N Kalit: PEHSVUKQDJULKE-UHFFFAOYSA-N^N InChI = 1 / C6H10N4S / c7-6 (8) 11-2-1-5-3-9-4-10-5 / h3-4H, 1-2H2, (H3,7,8) (H, 9, 10) Kalit: PEHSVUKQDJULKE-UHFFFAOYAJ
Jilmayganlar C1 = C (NC = N1) CCSC (= N) N S (C (= [N @ H]) N) CCc1cnc [nH] 1
Xususiyatlari
Kimyoviy formulalar	C₆H₁₀N₄S
Molyar massa	170.2354 g / mol
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
N tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari

Imetit a gistamin H₃ retseptorlari agonist.^[1]

Adabiyotlar

^ Garbarg, M; Arrang, JM; Rouleau, A; Ligneau, X; Tuong, tibbiyot fanlari doktori; Shvarts, JK; Ganellin, CR (1992). "S-2- (4-imidazolil) etilizotiyourea, juda o'ziga xos va kuchli gistamin H3 retseptorlari agonisti". Farmakologiya va eksperimental terapiya jurnali. 263 (1): 304–10. PMID 1383495.

v t e Gistamin retseptorlari modulyatorlar
H₁	Agonistlar: 2-piridiletilamin Betaxistin Gistamin HTMT L-Histidin UR-AK49 Antagonistlar: Birinchi avlod: 4-metildifenhidramin Alimemazin Antazolin Azatadin Bamipin Benzatropin (benztropin) Bepotastin Bromazin Bromfeniramin Buklizin Captodiame Karbinoksamin Xlortsiklizin Xloropiramin Xloroten Xlorfenamin Xlorfenoksamin Sininarizin Klemastin Klobenzepam Klocinizin Kloperastin Siklizin Siproheptadin Dacemazine Dekloksizin Deptropin Deksbromfeniramin Deksxlorfeniramin Dimenhidrinat Dimetindene Difengidramin Difenilpiralin Doksilamin Embramin Etodroksizin Etibenzatropin (etilbenztropin) Etimemazin Fenetazin Flunarizin Histapirrodin Gomoxlortsiklizin Gidroksietilprometazin Gidroksizin Izoprometazin Izotipendil Meklozin Medrilamin Mepiramin (pirilamin) Mequitazin Metafurilen Metapirilen Metdilazin Moksastin Orfenadrin Oksatomid Oksomemazin Perlapin Fenindamin Feniramin Feniltoloksamin Pimeteksen Piperoksan Pipoksizin Prometazin Propiomazin Pirrobutamin Talastin Tenalidin Tenildiamin Tiazinamium Tonzilamin Tolpropamin Tripelennamin Triprolidin Ikkinchi / uchinchi avlod: Akrivastin Alinastin Astemizol Azelastin Bamirastin Barmastin Bepiastin Bepotastin Bilastin Kabastinen Karbastin Cetirizine Klemastin Klemizol Klobenztropin Desloratadin Dorastin Ebastin Efletirizin Emedastin Epinastin Feksofenadin Flezelastin Ketotifen Latrepirdin Levokabastin Levotsetirizin Linetastin Loratadin Mapinastin Mebhidrolin Mizolastin Moksastin Noberastin Oktastin Olopatadin Perastin Pibaksizin Piklopastin Quifenadin (fenkarol) Rokastin Rupatadin Setastin Sekifenadin (bikarfen) Talastin Temelastin Terfenadin Vapitadin Zepastin Boshqalar: Atipik antipsikotiklar (masalan, aripiprazol, asenapin, brekspiprazol, brilaroksazin, klozapin, iloperidon, olanzapin, paliperidon, ketiapin, risperidon, ziprasidon, zotepin) Fenilpiperazin antidepressantlar (masalan, gidroksifazodon, nefazodon, trazodon, triazoledion) Tetratsiklik antidepressantlar (masalan, amoksapin, loxapin, maprotilin, mianserin, mirtazapin, oksaprotilin) Trisiklik antidepressantlar (masalan, amitriptilin, butriptilin, klomipramin, desipramin, dozulepin (dotiepin), doksepin, imipramin, iprindol, lofepramin, nortriptilin, protriptilin, trimipramin) Odatda antipsikotiklar (masalan, xlorpromazin, flupentiksol, flüfenazin, loxapin, perfenazin, proxlorperazin, tioridazin, tiyotiksen) Noma'lum / saralanmagan: Azanator Belorizin Elbanizin Flotrenizin GSK1004723 Napaktadin Tagorizin Trelnarizin Trenizin
H₂	Agonistlar: Amtamin Betazol Dimaprit Gistamin HTMT Impromidin L-Histidin UR-AK49 Antagonistlar: Bisfentidin Burimamid Simetidin Dalkotidin Donetidin Ebrotidin Etintidin Famotidin Izolamtidin Lafutidin Lamtidin Lavoltidin (loxtidin) Lupitidin Metiamid Mifentidin Niperotidin Nizatidin Osutidin Oksmetidin Pibutidin Quisultazine (quisultidine) Ramixotidin Ranitidin Roksatidin Sufotidin Tiotidin Tuvatidin Venritidin Xaltidin Zolantidin
H₃	Agonistlar: a-metilhistamin Kipralizant Gistamin Imetit Immepip Immetridin L-Histidin Methimepip Proksifan Antagonistlar: A-349821 A-423579 ABT-239 ABT-652 AZD5213 Bavisant Betaxistin Burimamid Siproksifan Klobenpropit Konessin Quvnoq GSK-189254 Impentamin Iodofenpropit Irdabisant JNJ-5207852 NNC 38-1049 PF-03654746 Pitolisant SCH-79687 Tioperamid VUF-5681
H₄	Agonistlar: 4-metilhistamin a-metilhistamin Gistamin L-Histidin OUP-16 VUF-8430 Antagonistlar: JNJ-7777120 Mianserin Seliforant Tioperamid Toreforant VUF-6002
Shuningdek qarang: Retseptor / signalizatsiya modulyatorlari • Monoamin metabolizmining modulyatorlari • Monoaminni qaytarib olish inhibitörleri

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