WikiDer > Kinupramin

Kinupramin
Klinik ma'lumotlar
Marshrutlari; ma'muriyat	Og'zaki
ATC kodi	N06AA23 (JSSV) ;
Huquqiy holat
Huquqiy holat	Umuman olganda: ℞ (faqat retsept bo'yicha);
Farmakokinetik ma'lumotlar
Yo'q qilish yarim hayot	33 soat
Identifikatorlar
	IUPAC nomi (±) -11-xinuklidin-3-yl-5,6-dihidrobenzo [b] [1] benzazepin;
CAS raqami	31721-17-2;
PubChem CID	93154;
ChemSpider	84098;
UNII	29O61HFF4L;
KEGG	D07336;
ECHA ma'lumot kartasi	100.046.149
Kimyoviy va fizik ma'lumotlar
Formula	C21H24N2
Molyar massa	304.437 g · mol−1

Quinupramine

Kinupramin (tovar nomlari Kevopril, Kinupril, Adeprim, Quinuprine) a trisiklik antidepressant (TCA) da ishlatilgan Evropa davolash uchun depressiya.^[1]^[2]

Farmakologik jihatdan kinupramin ta'sir ko'rsatadi in vitro kuchli sifatida muskarin asetilkolin retseptorlari antagonist (antikolinerjik) va H₁ retseptorlari antagonist (antigistamin), o'rtacha 5-HT₂ retseptorlari antagonistva zaif serotonin va norepinefrinni qaytarib olish inhibitori.^[3] Bu uchun juda kam o'xshashlik mavjud a₁-adrenerjik, a₂-adrenerjik, b-adrenerjik, yoki D.₂ retseptorlari.^[3]

Klinik jihatdan quinupramin deb xabar beriladi rag'batlantiruvchi shunga o'xshash imipramin, desipraminva demeksiptilin.^[4] Buning o'zi deb taxmin qilish mumkin jonli ravishda metabolitlar norepinefrin va / yoki serotoninni qaytarib olishga quinupraminning o'ziga qaraganda kuchli ta'sir ko'rsatishi mumkin.^{[iqtibos kerak]}

Adabiyotlar

^ Shveytsariya farmatsevtika jamiyati (2000). Index Nominum 2000: Xalqaro dori-darmonlar katalogi (CD-ROM bilan kitob). Boka Raton: Medpharm ilmiy nashrlari. p. 908. ISBN 3-88763-075-0.
^ Xose Migel Vela; Helmut Buschmann; Yorg Xolenz; Antonio Parraga; Antoni Torrens (2007). Antidepressantlar, antipsikotiklar, anksiyolitiklar: kimyo va farmakologiyadan klinik qo'llanilishgacha. Vaynxaym: Vili-VCH. p. 248. ISBN 978-3-527-31058-6.
^ ^a ^b Sakamoto H, Yokoyama N, Kohno S, Ohata K (dekabr 1984). "Yangi trisiklik antidepressant - kinupraminning retseptorlari bilan bog'lanish profili". Yapon farmakologiya jurnali. 36 (4): 455–60. doi:10.1254 / jjp.36.455. PMID 6098759.
^ Kent, Anjela; M. Bilyard (2003). Uyqu: fiziologiya, tekshiruvlar va tibbiyot. Nyu-York: Kluwer akademik / Plenum. p. 233. ISBN 0-306-47406-9.

Bu dori ga tegishli maqola asab tizimi a naycha. Siz Vikipediyaga yordam berishingiz mumkin uni kengaytirish.

[isbn3-88763-075-0-1] Shveytsariya farmatsevtika jamiyati (2000). Index Nominum 2000: Xalqaro dori-darmonlar katalogi (CD-ROM bilan kitob). Boka Raton: Medpharm ilmiy nashrlari. p. 908. ISBN 3-88763-075-0.

[isbn3-527-31058-4-2] Xose Migel Vela; Helmut Buschmann; Yorg Xolenz; Antonio Parraga; Antoni Torrens (2007). Antidepressantlar, antipsikotiklar, anksiyolitiklar: kimyo va farmakologiyadan klinik qo'llanilishgacha. Vaynxaym: Vili-VCH. p. 248. ISBN 978-3-527-31058-6.

[pmid6098759-3] Sakamoto H, Yokoyama N, Kohno S, Ohata K (dekabr 1984). "Yangi trisiklik antidepressant - kinupraminning retseptorlari bilan bog'lanish profili". Yapon farmakologiya jurnali. 36 (4): 455–60. doi:10.1254 / jjp.36.455. PMID 6098759.

[isbn0-306-47406-9-4] Kent, Anjela; M. Bilyard (2003). Uyqu: fiziologiya, tekshiruvlar va tibbiyot. Nyu-York: Kluwer akademik / Plenum. p. 233. ISBN 0-306-47406-9.

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v t e Trisikliklar
Sinflar	Akridin Antrasen Dibenzazepin Dibenzotsiklohepten Dibenzodiazepin Dibenzotiazepin Dibenzotiepin Dibenzoksazepin Dibenzoksepin Fenotiazin Piridazinobenzoksazin Piridinobenzodiazepin Tioksanten
Antidepressantlar (TCAlar va TeCA)	7-OH-Amoksapin Amezepine Amineptin Amitriptilin Amitriptilinoksid Amoksapin Aptazapin Azepindol Azipramin Batelapin Butriptilin Sianopramin Tsiklazindol Tsiklopramin Sidoksepin Klomipramin Kotriptilin Siyanotiyepin Demeksiptilin Depramin (balipramin) Desipramin (desmetilimipramin) Desmetilklomipramin Desmetiltrimipramin Dibenzepin Dimetakrin Dozulepin (dotiepin) Doksepin Enprazepin Esmirtazapin Fantridon Fluotrasen Gepzidin Gomopipramol Imipramin Imipraminoksid Intriptilin Iprindol Ketipramin Litrasen Lofepramin Losindol Loksapin Maprotilin Mariptilin Mazindol Melitrasen Metapramin Mezepin Mianserin Mirtazapin Monometakrin Naranol Nitroksazepin Norbutriptilin Nordoksepin Northiaden (nordosulepin) Nortriptilin (noramitriptilin) Noksiptilin Octriptilin Opipramol Oksaprotilin Pipofezin Pirandamin Propizepin Protriptilin Kinupramin Setiptilin (teciptiline) Spiroksepin Tandamin Tampramin Tianeptin Tienopramin Trimipramin
Antihistaminiklar	Azatadin Bisulepin Klobenzepam Siproheptadin Dacemazine Deptropin Desloratadin Epinastin Etimemazin Fenetazin Gidroksietilprometazin Izoprometazin Izotipendil Ketotifen Latrepirdin Loratadin Mebhidrolin Mequitazin Metdilazin Olopatadin Oksomemazin Fenindamin Pimeteksen Prometazin Propiomazin Rupatadin Tiazinamium
Antipsikotiklar	Asetofenazin Alimemazin Amoksapin Asenapin Butaklamol Butaperazin Karfenazin (karfenazin) Karpipramin Xlorpromazin Xlorprotixen Tsiklindol Citatepin Klokapramin Klomakran Klorotepin Clotiapine Klozapin Siyanotepin Dlotlotepin Dokloksitepin Erizepin Flukindol Flumezapin Fluotrasen Flupentiksol Flüfenazin Gevotrolin Gomopipramol Izofloksitepin Levomepromazin / Metotrimeprazin Loksapin Lurasidon Maroksepin Meperatiyepin Mesoridazin Metiapin Metitepin Metoksepin Mosapramin Naranol Oktometotepin Olanzapin Oksiklotepin Oksiprotepin Pentiapin Peraditiyepin Perathiepin Perazin Perfenazin Periciazin Pinoksepin Piperatsetazin Pipotiazin Pikindon Proxlorperazin Promazin Protipendil Ketiapin Savoksepin / sipazoksapin Sulforidazin Tenilapin Tietilperazin Tiyopropazat Tioridazin Thiothixene Tilozepin Traboksopin Trifluoperazin Triflupromazin Triflutepin Zotepin Zuklopentiksol
Antikonvulsanlar	Karbamazepin Dizosilpin Eslikarbazepin Eslikarbazepin asetat Etazepin Likarbazepin Okskarbazepin Oksitriptilin Rispenzepin
Boshqalar	Adozopin Aminopromazin Atiprosin Beloksepin Benzoktamin Carvedilol Sidoksepin Siklobenzaprin Damotepin Darenzepin Elanzepin Fluradolin Metilen ko'k Monatepil Nuvenzepin Oksetoron Perlapin P7C3 Pinadolin Pirenzepin Pirolat Pitrazepin Pizotifen Profenamin Serazapin Siltenzepin Telenzepin Tipindol Tropatepin Zolenzepin

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WikiDer > Kinupramin

Adabiyotlar

Klinik ma'lumotlar

Marshrutlari ma'muriyat	Og'zaki
ATC kodi	N06AA23 (JSSV)
Huquqiy holat
Huquqiy holat	Umuman olganda: ℞ (faqat retsept bo'yicha)
Farmakokinetik ma'lumotlar
Yo'q qilish yarim hayot	33 soat
Identifikatorlar
IUPAC nomi (±) -11-xinuklidin-3-yl-5,6-dihidrobenzo [b] [1] benzazepin
CAS raqami	31721-17-2
PubChem CID	93154
ChemSpider	84098
UNII	29O61HFF4L
KEGG	D07336
ECHA ma'lumot kartasi	100.046.149
Kimyoviy va fizik ma'lumotlar
Formula	C₂₁H₂₄N₂
Molyar massa	304.437 g · mol⁻¹